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临床试验/NCT04092426
NCT04092426Unknown不适用

Prevelance of Keratoconus in Individuals Attending Refreactive Surgery Centers in Assiut

Assiut University0 个研究点目标入组 300 人开始时间: 2019年10月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
300
主要终点
Prevalence of keratoconus in different areas in assiut

研究概览

简要总结

Keratoconus is a degenerative disease entity characterized by conical shape ectasia of the cornea. progressive conical deformation of the cornea leads to substantial astigmatism. Patients who are at an advanced stage of ectasia are often led to corneal transplant or other treatments, which essentially aim at correcting the refractive error and not in treating the ectasia. The top of the protruding cone that corneal configuration may be close to the visual axis or below and nasal of that. The disease manifests during adolescence, followed by slow progressive course, although it is possible to stabilize anytime. In 85% of cases both eyes are affected, but the severity of the attack can present significant asymmetry.

详细描述

Often in keratoconus a positive family history is present. Prevelance of keratoconus varies greatly worldwide.The reported prevalence of keratoconus varies widely depending upon the geographic location, diagnostic criteria used, and the cohort of patients selected. Environmental factors may contribute to the wide variation in prevalence.

the Middle East have higher prevalence than locations with cooler climates and less sunshine

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • persons attending refractive surgery centers in Asssiut.
  • patients found to have keratoconus are included , based on history , clinical examination and corneal topography
  • Exclusion criteria :
  • patients not attending those refractive surgery centers.
  • patients attending these centers but not diagnosed to be keratoconus .
  • Pregnancy or breastfeeding

排除标准

  • 未提供

结局指标

主要结局

Prevalence of keratoconus in different areas in assiut

时间窗: one year

Number of keratoconus cases detected areas in indivduals attending refractive surgery centers in Assiut

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mariam hamdy

principal investigator

Assiut University

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