Prevelance of Keratoconus

• Conditions: Keratoconus
• Interventions: Other: opthalmologic examination

• Registration Number: NCT04092426
• Lead Sponsor: Assiut University

Brief Summary

Keratoconus is a degenerative disease entity characterized by conical shape ectasia of the cornea. progressive conical deformation of the cornea leads to substantial astigmatism. Patients who are at an advanced stage of ectasia are often led to corneal transplant or other treatments, which essentially aim at correcting the refractive error and not in treating the ectasia. The top of the protruding cone that corneal configuration may be close to the visual axis or below and nasal of that. The disease manifests during adolescence, followed by slow progressive course, although it is possible to stabilize anytime. In 85% of cases both eyes are affected, but the severity of the attack can present significant asymmetry.

Detailed Description

Often in keratoconus a positive family history is present. Prevelance of keratoconus varies greatly worldwide.The reported prevalence of keratoconus varies widely depending upon the geographic location, diagnostic criteria used, and the cohort of patients selected. Environmental factors may contribute to the wide variation in prevalence.

the Middle East have higher prevalence than locations with cooler climates and less sunshine

Study Timeline

• Status Verified: 2019-09
• Study First Submitted: 2019-09-15
• Study First Submitted QC: 2019-09-15
• Last Update Submitted: 2019-09-15
• Study First Posted: 2019-09-17
• Last Update Posted: 2019-09-17
• Study Start: 2019-10-01
• Primary Completion: 2020-10-01
• Study Completion: 2021-10-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

1. persons attending refractive surgery centers in Asssiut.
2. patients found to have keratoconus are included , based on history , clinical examination and corneal topography

Exclusion criteria :

1. patients not attending those refractive surgery centers.
2. patients attending these centers but not diagnosed to be keratoconus .
3. Pregnancy or breastfeeding

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
patients with keratoconus	opthalmologic examination	patients with keratoconus attending refractive surgery centers in Assiut will be subjected to the following :- 1. Full history and clinical evaluation. 2. collection of individual data ( residency , occupation , special habbit , chronic illness ) 3. Analysis of results to assess prevelance of keratoconus and its distribution geographically in Assiut

Primary Outcome Measures

Name	Time	Method
Prevalence of keratoconus in different areas in assiut	one year	Number of keratoconus cases detected areas in indivduals attending refractive surgery centers in Assiut