A study to test the effects of walking and weight lifting on blood glucose, muscle strength, energy utilization, total fat and muscle content within body among Indians with prediabetes
- Registration Number
- CTRI/2018/05/014100
- Lead Sponsor
- Dr Pranathi R
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
BMI:18.5-30kg/m2
Impaired oral glucose tolerance test and fasting plasma glucose(prediabetes: FBS 101-125mg/dl, PPBS 141-199 mg/dl, HbA1c 5.7-6.4%)
Normal oral glucose tolerance test and fasting plasma glucose(controls: FBS <100 mg/dl, PPBS <140 mg/dl, HbA1C <5.7%)
1. Presence of chronic diseases (i.e., hypertension, tuberculosis, cancer, chronic renal failure, ischemic heart disease etc.,)
2. Any form of anemia
3. Any form of peripheral neuropathy
4. Muscular dystrophies
5. Any form of joint injuries or surgeries (knee and wrist)
6. History of osteoarthritis
7. Weight loss greater than 2 Kg in the past 6 months
8. Physical activity level > 1.75
9. Any history of chronic alcohol intake or tobacco consumption including cigarettes
10. Retinopathy
11. Any form of surgeries
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Glycated hemoglobinTimepoint: baseline and after 12 weeks intervention
- Secondary Outcome Measures
Name Time Method Insulin sensitivity and beta cell functions, <br/ ><br>Muscle quality, <br/ ><br>Body composition, <br/ ><br>mRNAs of intracellular signaling pathway <br/ ><br> <br/ ><br>Timepoint: baseline and after 12 weeks intervention