A577-nm Pro -Yellow Laser In Treatment of Striae Rubra
Overview
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Al-Azhar University
- Enrollment
- 18
- Locations
- 1
- Primary Endpoint
- dermoscopic change of width of striae rubrae
Overview
Brief Summary
Stretch marks or striae are common skin condition occurring in both genders, but they are more prevalent among women. These are linear dermal scars that are accompanied by epidermal atrophy. They usually occur frequently in numerous physiological and pathological conditions, such as adolescent growth, pregnancy, obesity, Cushing disease, Marfan syndrome, and long-term systemic or topical steroid use. Decreased expression of collagen and fibronectin genes has also been associated with striae.
The pro-yellow laser systems can be used in a wide range of indications such as facial erythema, facial telangiectasia, port wine stain nevus, rosacea, poikilo derma civatte, and Becker's nevus
Some of these indications are clinical lesions in the vascular pattern; some are related to the factors that trigger vascularity, such as vascular endothelial growth factor (VEGF) in etiopathogenesis
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •.Patients diagnosed with striae rubera. .Age groups: at any age. .Sex : ( females).
- •Co-operative patient
Exclusion Criteria
- •Pregnancy .
- •Patient using drugs exacerbating stria as topical or systemic steroid, and patients using other forms of treatment for stria as topical tretinoin, emollients, glycolic acid peel and laser, because that might affect the result of our study.
- •Stria Alba.
- •Skin infection (viral, bacterial or parasitic).
- •Immunosuppressed patients or with history of malignancy or radiation therapy and chronic debilitating diseases and Cushing syndrome.
- •Hypersensitivity to light and intak of photosensitizing drugs.
Outcomes
Primary Outcomes
dermoscopic change of width of striae rubrae
Time Frame: 1 year
dermoscopic photo for width of striae
Secondary Outcomes
No secondary outcomes reported
Investigators
Soha Alaa Abdelaal
resident doctor atD dermatology department
Al-Azhar University