Evaluation of COVID-19 assessment in emergency departments and ambulance services
- Conditions
- COVID-19 (SARS-CoV-2 infection)Infections and Infestations
- Registration Number
- ISRCTN28342533
- Brief Summary
2020 Results article in https://pubmed.ncbi.nlm.nih.gov/33273040/ post-exertion oxygen saturation sub-study results (added 07/12/2020) 2020 Results article in https://pubmed.ncbi.nlm.nih.gov/33237907/ results (added 15/01/2021) 2021 Preprint results in https://doi.org/10.1101/2021.01.23.21249978 non-peer-reviewed analysis of DNAR status in preprint (added 19/03/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33481930/ triage tool development results (added 19/03/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33961960/ secondary analysis results (added 10/05/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34083427/ (added 07/06/2021) 2021 Preprint results in https://doi.org/10.1101/2021.07.27.21261031 Prognostic accuracy study results (added 30/07/2021) 2021 Preprint results in https://doi.org/10.1101/2021.10.12.21264136 Observational cohort study results (added 21/10/2021) 2021 Preprint results in https://doi.org/10.1101/2021.06.24.21259441 Accuracy of telephone triage (added 03/12/2021) 2021 Preprint results in https://doi.org/10.1101/2020.09.01.20185793 Prognostic accuracy results for children (added 03/12/2021)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 22445
All adults and children with suspected respiratory infection during a pandemic who present at the emergency department of a participating hospital, call 111 or 999 services or are attended by a 999 ambulance from a participating ambulance trust.
Patients will be eligible for inclusion if they meet the current clinical diagnostic criteria;
1. Fever (pyrexia =38°C) or a history of a fever
2. Influenza-like illness (two or more of cough, sore throat, rhinorrhoea, limb or joint pain, headache, vomiting or diarrhoea or severe and/or life-threatening illness suggestive of an infectious process. (Or if they meet any future clinical diagnostic criteria recommended by the Department of Health).
Participants will only be excluded from the study if they request to be.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patients who die or require respiratory, cardiovascular or renal support will be defined as having an adverse outcome. If patients survive to 30 days without requiring respiratory, cardiovascular or renal support they will be defined as having no adverse outcome. If a severe pandemic leads to hospital resources being overwhelmed the researchers will categorise patients as having an adverse outcome if they were deemed to have needed respiratory, cardiovascular or renal support but were denied this due to lack of resources; Timepoint(s): 30 days
- Secondary Outcome Measures
Name Time Method There are no secondary outcome measures