Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment of Sever Acne

Phase 1

Completed

• Conditions: Acne

• Registration Number: NCT00416585
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne

Detailed Description

few studies has been done of serum levels Ca, P, PTH and vitamin D metabolites in patients receiving isotretinoin .In this study we measured serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne in 30 patients . the patients had no kown skeletal, endocrine ,renal and gastrointestinal disorders.

Study Timeline

• Study Start: 2005-10
• Study Completion: 2006-11
• Study First Submitted: 2006-12-27
• Study First Submitted QC: 2006-12-27
• Study First Posted: 2006-12-28
• Status Verified: 2008-01
• Last Update Submitted: 2008-01-22
• Last Update Posted: 2008-01-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• sever acne

Exclusion Criteria

• renal disorders
• gastrointestinal disorders
• skeletal disorders
• endocrine disorders
• drugs such as glucocorticoids , thiazide diuretics, mineral multivitamins, anti acids, tetracyclines

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray before the treatment

Secondary Outcome Measures

Name	Time	Method
serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray after the treatment

Trial Locations

Locations (1)

Shaheed Beheshti Medical University, Skin research center; 🇮🇷 Tehran, Iran, Islamic Republic of