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Clinical Trials/NCT07512869
NCT07512869
Recruiting
Not Applicable

Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Implementation Study

Institute of HIV Research and Innovation Foundation, Thailand1 site in 1 country76 target enrollmentStarted: February 17, 2025Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Sponsor
Institute of HIV Research and Innovation Foundation, Thailand
Enrollment
76
Locations
1
Primary Endpoint
Substance use-related harm assessed by self-administered questionnaire

Overview

Brief Summary

This study evaluates the pre-implementation phase of a host-led harm reduction model for men who have sex with men (MSM) engaging in chemsex in Bangkok, Thailand, focusing on understanding harms, contexts, and needs to develop a tailored intervention.

Detailed Description

HAMMOCK is a cross-sectional mixed-methods study designed to explore chemsex practices among MSM, including both hosts and guests, as well as key stakeholders such as CSOs, hospital staff, and police.

The study aims to:

  • Explore substance-related, sexual health, mental health, and socio-legal harms
  • Understand the context and dynamics of private chemsex parties
  • Co-develop a novel host-led harm reduction model
  • Identify barriers and facilitators to implementation The study includes both quantitative (self-administered questionnaires) and qualitative (in-depth interviews) components and follows a two-phase approach: exploration and preparation phases under the EPIS framework.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Other

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
Male
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • MSM aged ≥18 years
  • Able to communicate in Thai
  • Specific by group:
  • Chemsex hosts: hosted ≥2 times in past 6 months
  • Chemsex guests: attended ≥2 times in past 6 months
  • CSO / hospital / police staff: working ≥3 months in related roles
  • Provide informed consent

Exclusion Criteria

  • Unable to provide informed consent (e.g., under substance influence at consent)

Arms & Interventions

Single Arm - Mixed-method Harm Reduction Model Development

Participants (chemsex party hosts, guests, CSO staff, hospital staff, and police officers) will participate in a mixed-method study consisting of two phases (Exploration and Preparation) to assess harms related to chemsex and to develop and refine a novel harm reduction model for private chemsex party settings.

Intervention: Self-administered questionnaire assessment (Behavioral)

Single Arm - Mixed-method Harm Reduction Model Development

Participants (chemsex party hosts, guests, CSO staff, hospital staff, and police officers) will participate in a mixed-method study consisting of two phases (Exploration and Preparation) to assess harms related to chemsex and to develop and refine a novel harm reduction model for private chemsex party settings.

Intervention: Semi-structured in-depth interviews (IDIs) (Behavioral)

Single Arm - Mixed-method Harm Reduction Model Development

Participants (chemsex party hosts, guests, CSO staff, hospital staff, and police officers) will participate in a mixed-method study consisting of two phases (Exploration and Preparation) to assess harms related to chemsex and to develop and refine a novel harm reduction model for private chemsex party settings.

Intervention: Development and refinement of harm reduction model (Behavioral)

Outcomes

Primary Outcomes

Substance use-related harm assessed by self-administered questionnaire

Time Frame: Baseline (during Exploration phase, prior to model development)

Substance-related harms will be assessed using a structured self-administered questionnaire. The assessment includes: * Patterns of substance use (snorting, injecting, ingesting, anal insertion) * Frequency of use * Physical harms (e.g., injection-related injuries, overdose) * Psychological harms (e.g., substance dependence) This is a descriptive assessment; no composite scale score is generated.

Sexual health risk behaviors assessed by self-administered questionnaire

Time Frame: Baseline (during Exploration phase, prior to model development)

Sexual health risks will be assessed using a structured questionnaire including: * Number of sexual partners * Condom use * HIV/STI testing history * Self-reported HIV status * Pre-exposure prophylaxis (PrEP) use and adherence * Antiretroviral therapy (ART) adherence among participants living with HIV This is a descriptive assessment; no composite scale score is generated.

Depression severity assessed by Patient Health Questionnaire-9 (PHQ-9)

Time Frame: Baseline (during Exploration phase, prior to model development)

Depression will be assessed using the Patient Health Questionnaire-9 (PHQ-9): * Score range: 0 to 27 * Interpretation: * 0-4: Minimal depression * 5-9: Mild * 10-14: Moderate * 15-19: Moderately severe * 20-27: Severe Higher scores indicate worse depression severity

Anxiety severity assessed by Generalized Anxiety Disorder-7 (GAD-7)

Time Frame: Baseline (during Exploration phase, prior to model development)

Anxiety will be measured using the Generalized Anxiety Disorder-7 (GAD-7): * Score range: 0 to 21 * Interpretation: * 0-4: Minimal * 5-9: Mild * 10-14: Moderate * 15-21: Severe Higher scores indicate worse anxiety

Secondary Outcomes

  • Perceived stigma and socio-legal harm assessed by structured questionnaire(Baseline (during Exploration phase, prior to model development))

Investigators

Sponsor
Institute of HIV Research and Innovation Foundation, Thailand
Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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