Efficacy of Nasojejunal Enteral Feeding in Critically Ill Patients.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Efficacy of feeding
研究概览
简要总结
The purpose of this study is to determine if naso-jejunal feeding (feeding beyond the stomach) improves the efficacy of enteral feeding (feeding into the gut) in critically ill patients.
The study hypothesis is that in patients who fail to establish enteral feeding via the nasogastric route, introduction of nasojejunal feeding will lead to more effective enteral feeding than the current regime involving staged introduction of promotility agents.
详细描述
The study examines the area of enteral feeding in critically ill patients. Current standard enteral feeding practice is via a nasogastric with the addition of promotility agents for patients who fail to absorb their enteral nutrition.
This study compares the efficacy of nasojejunal feeding feeding with nasogastric enteral feeding with the addition of promotility agents.
The duration of feeding will be determined by the patients nutritional requirements and their general condition. However the data will be collected for duration of enteral feeding, 28 days or ICU discharge whichever occurs first.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients (18years or over) admitted to the ICU with an expected stay of more than 48 hours.
- •Patients commenced on enteral feeding via a nasogastric tube who fail to tolerate gastric feeding due to excessive gastric aspirate volumes.
- •Patients who consent or if the patient is incompetent, the next of kin, who consent, to inclusion in the study.
排除标准
- •patients less than 18 years of age.
- •Patients with known allergy to promotility agents, metoclopramide or erythromycin.
- •Patients with a contra indication to nasojejunal feeding. -
结局指标
主要结局
Efficacy of feeding
时间窗: participants will be followed until death, discharge from ICU, commencement of oral or parental nutrition or 28 days post ICU admission
次要结局
- 1. To determine the incidence of complications with enteral feeding via nasogastric and nasojejunal routes.(participants will be followed until death, discharge from ICU, commencement of parental or oral nutrition or 28 days post ICU admission.)
- 2. To assess the efficacy of current strategies for optimising enteral feeding efficacy.(participants will be followed until death, discharge from ICU commencement of oral or parental nutrition,or 28 days post ICU admission.)