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临床试验/NCT01516021
NCT01516021已完成不适用

Fat Intake Modulates Cerebral Blood Flow in Homeostatic and Gustatory Brain Areas in Humans

University Hospital Tuebingen2 个研究点 分布在 1 个国家目标入组 11 人开始时间: 2011年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
11
试验地点
2
主要终点
Changes in Cerebral Blood Flow due to the high or low fat yoghurt intake after 30 minutes and 120 minutes compared to a baseline measurement 30 minutes before yoghurt intake.

研究概览

简要总结

The aim of the current study was to investigate the effect of a high versus a low fat meal (operationalized by high and low fat yoghurt) on homeostatic and gustatory brain regions.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
25 Years 至 32 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • 未提供

排除标准

  • lactose intolerance
  • fMRI contraindications (metal implants,...)

结局指标

主要结局

Changes in Cerebral Blood Flow due to the high or low fat yoghurt intake after 30 minutes and 120 minutes compared to a baseline measurement 30 minutes before yoghurt intake.

时间窗: 30 minutes before as well as 30 minutes and 120 minutes after fat intake

We were interested in differential brain activations due to the high or low fat meal. To assess this, the mentioned time points are suitable. The Cerebral Blood Flow is measured using Arterial Spin Labeling sequences in a functional magnetic resonance tomography.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sabine Frank

Principal Investigator

University Hospital Tuebingen

研究点 (2)

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