Watch Laser Acupuncture With Nasal Radiation for Prevention of Coronary Artery Disease

Not Applicable

Completed

• Conditions: Cardiovascular Risk Factor; Coronary Artery Disease
• Interventions: Device: low level laser hemotherapy

• Registration Number: NCT03454594
• Lead Sponsor: Cairo University

Brief Summary

This study will evaluate the effect of low level laser blood radiation applied to all participants for prevention of coronary artery disease in patients with high risk (hypertension,high blood viscosity, hypercholesterolemia as well as related immune issues)

Detailed Description

The areas of low - intensity laser use have expanded in several conditions by different mechanisms and ways. Hypertension as one of coronary artery disease risk factors and early indicator of future cardiovascular events with high blood viscosity and elevated blood cholesterol levels with immune-pathological basis became necessary issue to be handled. Low Level Laser irradiation effects on blood is very essential way in revealing the mechanisms of the action of laser radiation on biological tissues by means of changes in metabolism, leading to molecular, cellular and systemic changes.

Study Timeline

• Study First Submitted: 2018-02-25
• Study First Submitted QC: 2018-03-03
• Study First Posted: 2018-03-06
• Study Start: 2018-05-01
• Primary Completion: 2018-08-05
• Study Completion: 2018-12-30
• Status Verified: 2019-02
• Last Update Submitted: 2019-02-05
• Last Update Posted: 2019-02-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

• stage I hypertensive patients
• patients from 30 to 34.9 kg/m2 body mass index
• medically stable patients
• all participants have sufficient cognition enough to understand the requirements of the study

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Exclusion Criteria

• history of malignant disease
• smoking
• history of progressive fatal disease
• history of drug or alcohol abuse
• blood donation within at least 30 days
• pregnant, trying to be pregnant or breast feeding
• cognitive impairment that will make it difficult to partake in the study

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
low level laser hemotherapy	low level laser hemotherapy	Watch laser acupuncture and nasal irradiation

Primary Outcome Measures

Name	Time	Method
changes of blood pressure	8 weeks	measuring blood pressure before and after each low level laser radiation

Secondary Outcome Measures

Name	Time	Method
change in functional capacity	70 days	measuring of 6 minute walking test before and after low level laser irradiation as an indicator of functional capacity improving
change in CD 8 (cluster of differentiation 8) level	45 days	measuring changes in CD 8 (cluster of differentiation 8) level before and after low level laser radiation session
change in TC (total cholesterol) level	60 days	measuring changes in TC (total cholesterol) level before and after low level laser radiation session
change in LDL (low density lipoprotien) level	60 days	measuring changes in LDL (low density lipoprotien) level before and after low level laser radiation session
change in TG (triglyceride) level	60 days	measuring changes in TG (triglyceride) level before and after low level laser radiation session
change in HDL (high density lipoprotien) level	60 days	measuring changes in HDL (high density lipoprotien) level before and after low level laser radiation session
changes in blood viscosity	8 weeks	measuring changes in blood viscosity before and after low level laser radiation session
change in IL-17 level	45 days	measuring changes in IL-17 level before and after low level laser radiation session

Trial Locations

Locations (1)

Cairo; 🇪🇬 Giza, Dokki, Egypt