临床试验/NCT02136836

NCT02136836Unknown不适用

Investigation of the Proportion of Human Epidermal Growth Factor Receptor 2 Protein Overexpression of Gastric Adenocarcinoma and Prognostic Effect of HER2, and Analysis of Practice Pattern of Herceptin Use in Stage IV Gastric Cancer

Yonsei University1 个研究点分布在 1 个国家目标入组 860 人开始时间: 2014年5月最近更新: 2014年5月13日

适应症

试验速览

阶段: 不适用
发起方: Yonsei University
入组人数: 860
试验地点: 1
主要终点: The proportion of HER2 overexpression in gastric cancer patients

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The objective of this study is to investigate the proportion of HER2 overexpression in gastric cancer patients group, to evaluate the relation of HER2 overexpression with prognosis, and to analyze the proportion of herceptin applied to patients in clinical field. Furthermore, the investigators are going to reevaluate the clinical benefit of Herceptin for survival prolongation compared to chemotherapy only.

研究设计

研究类型: Observational
观察模型: Case Only
时间视角: Retrospective

入排标准

性别: All
接受健康志愿者: 否

入选标准

•Histologically confirmed gastric adenocarcinoma
•Patients were diagnosed during 2006-2013
•HER2 expression status was evaluated in primary gastric cancer or metastatic lesion.

排除标准

•Patients with second primary cancer within 5 years

结局指标

主要结局

The proportion of HER2 overexpression in gastric cancer patients

时间窗: 8 years

次要结局

Gastric cancer specific survival according to HER2 expression in each stage(5 years)

研究者

发起方

Yonsei University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Jae Yong Cho

Chief of division of medical oncology, Gangnam Severance Hospital

Yonsei University

研究点 (1)

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