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Clinical Trials/NCT03482427
NCT03482427
Unknown
N/A

Assessing the Healthy Heart Score Intervention In the Primary Care Setting as a Primordial Prevention Tool

Ohio University1 site in 1 country100 target enrollmentMarch 19, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cardiovascular Diseases
Sponsor
Ohio University
Enrollment
100
Locations
1
Primary Endpoint
Changes in the overall Healthy Heart Score risk score
Last Updated
8 years ago

Overview

Brief Summary

In this pilot study, the investigators will assess the clinical utility and feasibility of the Healthy Heart Score in the primary clinical care setting for the primordial prevention of cardiovascular disease. The investigators will conduct a randomized clinical trial to test the lifestyle intervention based on the Healthy Heart Score compared to usual care. The aim is to include 100 participants (50 in each group). Each participant will complete 2 visits (initial and a follow up visit after 12 weeks).

Detailed Description

Created by the Harvard T.H Chan School of Public Health, the Healthy Heart Score is a previously validated online risk calculator that determines the 20-year Cardiovascular Disease ) risk based on 9 modifiable lifestyle factors including; smoking habits, body mass index, physical activity, alcohol consumption, fruit and vegetables intake, cereal fiber, nuts, sugar-sweetened beverages, and red meat, and processed meats consumption. In this pilot study, the investigators will assess the clinical utility and feasibility of the Healthy Heart Score in the primary clinical care setting for the primordial prevention of cardiovascular disease. The investigators will conduct a clinical trial to test our intervention compared to usual care. The investigators will conduct a randomized clinical trial to test the lifestyle intervention based on the Healthy Heart Score compared to usual care. The aim is to include 100 participants (50 in each group). Each participant will complete 2 visits (initial and a follow up visit after 12 weeks).

Registry
clinicaltrials.gov
Start Date
March 19, 2018
End Date
April 30, 2019
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mercedes Sotos Prieto, PhD

Assistant Professor

Ohio University

Eligibility Criteria

Inclusion Criteria

  • 18 years of age or older, No cardiovascular diagnosis, Body Mass Index \> 25 and/or having at least one of the following clinical risk factors: elevated blood pressure, pre-high cholesterol, pre-diabetes but not currently taking medications for the previous conditions.

Exclusion Criteria

  • Those not meeting the inclusion criteria and women who are pregnant or planning to get pregnant.

Outcomes

Primary Outcomes

Changes in the overall Healthy Heart Score risk score

Time Frame: 12-weeks

The Healthy Heart Score is a lifestyle-based risk tool that estimates 20-year CVD risk (https://healthyheartscore.sph.harvard.edu/) This gender-specific algorithm has been published (DOI: 10.1161/JAHA.114.000954): 20-year CVD risk (%) "Healthy Heart Score" = \[1 - 0. 9660 (exp \[W- 6.57301)\] × 100% where W= 0.10820 x age + 0.15285 (if past smoker) + 0.90138 (if current smoker) + 0.04676 × BMI - 0.01923 × grams/d of alcohol + 0.0004 × (grams/d of alcohol)2- 0.029251 × hours/week of physical activity - 0.05113 × diet score\* 20-year CVD risk (%) "Healthy Heart Score" = \[1 - 0. 96368 (exp \[W-7.2437)\] × 100% where W= 0.13580 x age- 0.0005 x (age)2 + 0.06979 (if past smoker) + 0.42305 (if current smoker) +0.07424 × BMI - 0.00898 × grams/d of alcohol + 0.0001 × (grams/d of alcohol)2- 0.01755 × hours/week of physical activity - 0.06691 × diet score

Changes in the overall composite of diet

Time Frame: 12-weeks

women: Diet score = (0.03626 × grams/d of cereal fiber + 0.18283 \[if fruits + vegetables ≥3 servings/d\] + 0.14522 \[if nuts 0.1-1 servings/d + 0.2444 \[if nuts \>1 servings/d\]- 0.14631 × servings/d of sugar-sweetened beverages - 0.15624 × servings/d of red and processed meats)\*10 Women: Diet score = (0.03626 × grams/d of cereal fiber + 0.18283 \[if fruits + vegetables ≥3 servings/d\] + 0.14522 \[if nuts 0.1-1 servings/d + 0.2444 \[if nuts \>1 servings/d\]- 0.14631 × servings/d of sugar-sweetened beverages - 0.15624 × servings/d of red and processed meats)\*10. Men: where W= 0.13580 x age- 0.0005 x (age)2 + 0.06979 (if past smoker) + 0.42305 (if current smoker) +0.07424 × BMI - 0.00898 × grams/d of alcohol + 0.0001 × (grams/d of alcohol)2- 0.01755 × hours/week of physical activity - 0.06691 × diet score\*

Changes in fruit and vegetables intake

Time Frame: 12-weeks

servings/day

Changes in red and processed meats intake

Time Frame: 12-weeks

servings/week

Changes in sugar and sweetened beverages

Time Frame: 12-weeks

servings/week

Changes in nut consumption

Time Frame: 12-weeks

servings week

changes in alcohol consumption

Time Frame: 12-weeks

g/day

changes in cereal fiber

Time Frame: 12-weeks

g/day

changes in body mass index

Time Frame: 12-weeks

kg/m2

Changes in physical activity

Time Frame: 12-weeks

hours per week

Secondary Outcomes

  • Changes in diastolic blood pressure(12-weeks)
  • changes in percentage of body fat(12-weeks)
  • changes in body weight(12-weeks)
  • Changes in total cholesterol levels(12-weeks)
  • Changes in triglycerides levels(12-weeks)
  • Changes in Low Density Protein levels(12-weeks)
  • Changes in High Density Protein levels(12-weeks)
  • Changes in Hemoglobin glycosylated levels(12- weeks)
  • Changes in systolic blood pressure(12-weeks)

Study Sites (1)

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