Fatigue in patients with primary Sjogren’s syndrome
Not yet recruiting
- Conditions
- Primary Sjögren's syndrome (pSS)FatiguefMRICytokinesPrimaire syndroom van SjögrenVermoeidheidfMRICytokines
- Registration Number
- NL-OMON24290
- Lead Sponsor
- niversity Medical Center Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Both patients and control subjects:
- Age: 18-65 years
Exclusion Criteria
Both patients and control subjects:
- Drug or alcohol addicition
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Maximal force of the first dorsal interosseous (FDI) muscle<br /><br>- Force decline during the fatiguing task<br /><br>- Muscle activation during the fatiguing task<br /><br>- Questionnaire scores<br /><br>- Changes in cortical activation during the fatiguing task (functional MRI data).
- Secondary Outcome Measures
Name Time Method - Ectromyographic activity of the FDI muscle during the motor tasks