Efficacy and Safety of Modified Gegenqinlian Fomular for Advanced Colorectal Cancer (Damp Heat Accumulation Type): A Multicenter Randomized Controlled Trial
- Conditions
- advanced colorectal cancer
- Registration Number
- ITMCTR2100005267
- Lead Sponsor
- Shanxi Provincial Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Age > 18 years old, survival period >= 3 months;
2. Patients with colorectal cancer who meet the above-mentioned diagnostic criteria of Western medicine and TCM syndrome types, and have been diagnosed by definite pathology or cytology;
3. TNM stage is IV, patients with postoperative recurrence, metastasis or lost the opportunity for surgery without surgery, have not taken traditional Chinese medicine within the past 1 month;
4. No other primary tumors and serious heart, liver and kidney diseases;
5. Those who have follow-up telephone numbers and addresses, patients or their families who are willing to cooperate with follow-up visits, have relatively complete medical records, and sign informed consent.
1. Non-primary colorectal cancer;
2. Those who are unable or unwilling to accept traditional Chinese medicine treatment;
3. The patient has developed intestinal obstruction and cannot take drugs, needs intravenous high-energy nutrition, or has malabsorption syndrome or other diseases that affect the absorption of the gastrointestinal tract, or has active peptic ulcer disease.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of Life;progression-free survival;overall survival;TCM symptom score;
- Secondary Outcome Measures
Name Time Method tumor makers;immune state;Karnofsky functional status score;size of tumor;tumor microenvironment;