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Study the effect of Empagliflozin in type 2 diabetic patients

Phase 3
Conditions
Condition 1: Diabetes. Condition 2: Heart disease.
Type 2 diabetes mellitus with other specified complication
E11.69
Registration Number
IRCT20210710051833N1
Lead Sponsor
Zanjan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
200
Inclusion Criteria

Type 2 diabetic patients (treated with oral hypoglycemic drugs) with STEMI (typical chest pain lasting more than 30 minutes during the 12 hours prior to admission, with ST-segment elevation above 0.1 mV in both Lead or more on ECG) who will be admitted to Ayatollah Mousavi Hospital in Zanjan between August and October 1401
Diabetic patients with MI who have previously received prior treatment with metformin, sulfonylureas, or a combination of these two drugs.

Exclusion Criteria

Cardiogenic shock
Hypoglycemia
Diabetic ketoacidosis
History of coronary artery bypass surgery
Type 1 diabetes
Severe liver failure
Patients with advanced cancer
History of severe hypersensitivity to empagliflozin or its components
Severe renal failure (eGFR <30 mL / minute / 1.73 m2), end-stage renal disease (ESRD) or dialysis
Hypovolemia
Any inflammatory disease being treated
History of any cancer
Advanced heart failure

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Mortality associated with cardiovascular events. Timepoint: Hospitalization time and one month and three months later. Method of measurement: Monthly face-to-face visits, tests and echoes.
Secondary Outcome Measures
NameTimeMethod
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