Tadalafil and Bosentan on pulmonary arterial pressure, cardiac outupt and prognosis of mechanical ventilation in COPD patients with pulmonary hypertenion under mechanical ventilatio
Phase 2
- Conditions
- Chronic obstructive pulmonary disease.Chronic obstructive pulmonary disease, unspecifiedJ44.9
- Registration Number
- IRCT20190325043107N24
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
History of COPD
Hospitalized in the pulmonary intensive care unit
Under controlled breathing or connected to a ventilator
Exclusion Criteria
Body mass index higher than 30
Lung cancer and any other type of cancer
Right and left ventricular dysfunction
Chest radiotherapy during the last month
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pulmonary function. Timepoint: Once every three days for three weeks. Method of measurement: Physical examination.
- Secondary Outcome Measures
Name Time Method