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Clinical Trials/NCT03254251
NCT03254251
Completed
Not Applicable

The Effects of a 12-week Stair Climbing Regimen on Arterial Stiffness, BP and Leg Strength in Stage-1 Hypertensive Postmenopausal Women

Pusan National University0 sites41 target enrollmentJanuary 9, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Menopause
Sponsor
Pusan National University
Enrollment
41
Primary Endpoint
Arterial stiffness
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

We used a parallel experimental design. Following an initial screening and familiarization session of study tests and procedures, eligible postmenopausal women were randomly assigned to a stair climbing (SC) group or non-exercising control group. SC training session was progressive program, and was performed 4 days a week for 12 weeks. Measurements were collected at baseline and after 12 weeks during the same time of day (±1 hour) in the morning following an overnight fast and abstinence from caffeinated drinks, alcohol, and between 48 and 72 hours after the last exercise session.

Registry
clinicaltrials.gov
Start Date
January 9, 2017
End Date
April 10, 2017
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Won-mok son

postdoctoral fellow

Pusan National University

Eligibility Criteria

Inclusion Criteria

  • Stage-1 hypertension
  • Postmenopausal

Exclusion Criteria

  • Pulmonary, renal, adrenal, pituitary, severe psychiatric, thyroid, or cardiovascular disease other than stage-1 systolic hypertension (140-159 mmHg)
  • Hormone replacement therapy during the 6 months prior the study
  • Smoker or having any medication changes in the previous year
  • Experience with psychological and physical therapy in the previous year
  • History of steady exercise or exercise training in the last year

Outcomes

Primary Outcomes

Arterial stiffness

Time Frame: 12 weeks

Arterial stiff ness was measured by brachial to ankle pulse wave velocity (baPWV, m/s) using volume plethysmographic device (VP-1000).

Muscle strength

Time Frame: 12 weeks

Muscle strength was measured by the eight repetition maximum (8RM) test using extension machine (Cyber 6000).

Heart rate (HR)

Time Frame: 12 weeks

Heart rate was measured by ECG

Body mass index (BMI)

Time Frame: 12 weeks

BMI was calculated as weight/height\^2 (kg/m\^2)

Body composition

Time Frame: 12 weeks

Body composition was measured using eight-polar tactile-electrode impedance meter (InBody 720). Body weight (kg), fat mass (kg), and fat free mass (kg) were assessed.

Blood pressure (BP)

Time Frame: 12 weeks

BP (mmHg) was measured by volume plethysmographic device. Diastolic blood pressure and systolic blood pressure were measured.

Height

Time Frame: 12 weeks

Height (m) was measured with a stadiometer

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