Prognostic Value of Pediatric GCS-Pupil Score in Pediatric Patients With Traumatic Brain Injury
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 128
- Locations
- 1
- Primary Endpoint
- Death rate
Study Overview
Brief Summary
There are studies reporting that the survival rate in pediatric patients with abnormal pupillary response is 23% and that pupillary response is effective on mortality and patient outcomes. Studies in the literature examining the effect of pupillary response on mortality and outcome in pediatric patients with traumatic brain injury reported that bilaterally dilated pupils were associated with a higher mortality rate.
Considering the literature results, we believe that obtaining the GCS-Pupil score by combining GCS and pupillary reaction in pediatric patients with traumatic brain injury will be effective in predicting patient outcomes.
Detailed Description
Obtaining a GCS-Pupil score using the total GCS score: 0 points are given for pupillary reaction if both pupils react to light, 1 point if one pupil does not react to light, and 2 points if both pupils do not react to light. Total GCS-P score is calculated by the formula of Eye Response + Verbal Response + Motor Response - Pupil Reaction and scores between 1-15.
In the study, the worst GCS and current pupillary light reaction score in the first 24 hours will be evaluated.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- — to 18 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Be under the age of 18,
- •Not having mental and motor developmental retardation,
- •Having had a traumatic brain injury,
- •Alive at admission and followed up for at least 24 hours
Exclusion Criteria
- •Eye trauma or severe facial trauma that will affect the assessment,
- •Those under deep sedation,
- •Those who have been administered drugs (Atropine and mydriatic) that will affect the pupillary response.
Outcomes
Primary Outcomes
Death rate
Time Frame: one year
Death
Secondary Outcomes
- Adverse functional outcomes(one year)
Investigators
AKİF BULUT
Principal Investigator
Uludag University