MedPath

Efficacy and safety of MePro in patients with pancreatic cancer

Phase 2
Recruiting
Conditions
Pancreatic cancer
Registration Number
JPRN-jRCTs031230331
Lead Sponsor
Takahashi Miwako
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
20
Inclusion Criteria

1. Subjects who are 18 years of age or older at the time of consent acquisition
2. Subjects who have been confirmed to have pancreatic cancer by histopathological or clinical examination
3. Subjects who have performed or are scheduled to perform [18F]FDG PET/CT by insurance within 30 days before or after the date of obtaining [11C] MePro PET/CT imaging, if [18F]FDG PET/CT imaging information is to be used
4. Subjects whose Performance Status (ECOG PS) is 0 or 1
5. Subjects who provide written informed consent

Exclusion Criteria

1. Subjects who have severe or progressive complications or subjects who have a history of these complications and are judged by the investigator or co-investigator to be unsuitable for this study
2. Subjects who have obvious abnormalities in physical and laboratory examinations (blood test and urinalysis) after obtaining the informed consent
3. Subjects with drug addiction or alcohol addiction
4. Subjects with mental illness or psychiatric symptoms who are judged to have difficulty in participating in this study
5. Subjects who are unable or restricted from the tests specified in the research plan
6. Subjects who are claustrophobic
7. Subjects who are considered to be inappropriate to participate in this study by the investigator or co-investigator

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The following points related to diagnostic performance will be evaluated and examined using PET/CT images including the pancreatic cancer lesion of [11C]MePro. <br># Ability to visualize pancreatic cancer <br># Administered radioactivity <br># Exploratory for the optimal conditions on PET imaging procedure
Secondary Outcome Measures
NameTimeMethod
1. Comparison of PET/CT images of the abdomen including pancreatic cancer lesions of [18F] FDG and the ability to visualize pancreatic cancer <br>2. Evaluation of adverse events<br>3. Examination of association with SLC6A20, a blood transporter protein
© Copyright 2025. All Rights Reserved by MedPath