eural and behavioral markers for the motivational negative symptoms of schizophrenia – a longitudinal approach - SyMoNe

Charité - Universitätsmedizin BerlinKlinik für Psychiatrie und Psychotherapie0 sites175 target enrollmentApril 5, 2017

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: F20
Sponsor: Charité - Universitätsmedizin BerlinKlinik für Psychiatrie und Psychotherapie
Enrollment: 175
Status: Completed
Last Updated: last year

No summary available.

Registry

who.int

Start Date

April 5, 2017

End Date

TBD

Last Updated

last year

Study Type

Observational

Sex

All

Sponsor

Charité - Universitätsmedizin BerlinKlinik für Psychiatrie und Psychotherapie

•In order to be eligible to participate in this study, all participants must meet all of the following criteria:
•18\-60 years old
•Written informed consent
•In patients the diagnostic criteria are:
•DSM\-5 diagnosis of schizophrenia on the basis of the Structured Clinical Interview for DSM\-5 (SCID\-I)
•Clinical stability as judged by the treating psychiatrist and indicated by no change in medication in the two weeks prior to the initial assessment

•Any potential subject who meets any of the following criteria will be excluded from participation in this study:
•Any previous neurosurgery or neurological disorder, including epilepsy
•History of head injury resulting in unconsciousness lasting at least 1 hour
•Pregnancy or lactation
•Any contraindications for MRI such as ferromagnetic/non\-MRI\-compatible items or medical devices on or in the body (for example pacemaker, brain stimulator, clips, metal implants)
•sensorineural hearing loss of 30dB or more or history of tinnitus
•Incompetency to fully comprehend the purpose of the study or to make a rational decision whether or not to participate
•In patients additional exclusion criteria are:
•Benzodiazepine use of more than 1mg lorazepam equivalents per day
•Comorbid axis\-I disorder