The effect of incretins to serum growth hormone levels in acromegalic patients during oral and intravenous glucose administration tests.
Not Applicable
- Conditions
- Acromegaly
- Registration Number
- JPRN-UMIN000006516
- Lead Sponsor
- Department of Medicine II, Hokkaido University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who do not agreed with written consent form. Patients who have the diseases, which may affect the result of endocrine tests, such as infectious, hepatic, and renal disorders. Poor controlled diabetic patients, because they are not appropriate for the glucose loading test. Patients who are inappropriate for this study by research director.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of the paradoxical increase of growth hormone in oral glucose tolerance test. Changes of serum growth hormone levels during intravenous glucose loading test and sitagliptin loading test in the patients with paradoxical growth hormone increase.
- Secondary Outcome Measures
Name Time Method Changes of serum growth hormone levels in pharmacological loading tests in the patients with or without the paradoxical increase.