Comparative Clinical Study Of Dexmedetomidine Vs Clonidine For Hemodynamic Stability
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/06/053563
- Lead Sponsor
- ARTI YADAV
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
ASA Physical status I and II
1. Patient refusal
2. History of laryngeal or tracheal surgery or pathology.
3. History of Bronchial asthma,
4. History of smoking, alcohol addiction or drug abuse.
5. Patients with coexisting systemic illness, morbid obese patient, neurological or psychological disease, hepatic or renal dysfunction, endocrinal or metabolic disorder.
6. Patients with hypertensive heart disease or on antihypertensives, beta blockers or calcium channel blockers.
7. Patient with known hypersensitivity or drug allergies.
8. Age less than 18 or more than 60.
9. Basal heart rate less than 60 and patient with heart block or with conduction defect.
10. Active upper respiratory tract infections.
11. Patients with difficult airway MP grade III and IV.
12. Pregnant or lactating female
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To evaluate and compare the intraoperative hemodynamic parameter with intravenous dexmedetomidine and intravenous clonidine as premedication during laproscopic surgeries under general anaesthesia.Timepoint: vital monitoring was done at baseline ,1 min before premedication ,1 min after premedication,1 min before induction,1 min after induction,1 min before intubation ,1 min after intubation,2 min,4 min,6 min,8 min ,10 min ,1 min after CO2 insufflation,after 15 min,at 5 min time interval up to 90 min .
- Secondary Outcome Measures
Name Time Method To evaluate Side effects of intravenous dexmedetomidine and clonidine.Timepoint: 1 min after giving drugs,2min,4min,6min,8min 10 min at 5 min time interval up to 90 min .