Comparative evaluation of MTA, combination of Chitosan-Nanohydroxyapatite and combination of Chitosan -Nanohydroxyapatite -Collagen on formation of dentinal bridge and inflammatory response of pulp when used as a direct pulp capping agent on human teeth.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- Asymptomatic vital permanent teeth with exposed pulp can be treated successfully by direct pulp capping using combination of chitosan-nanohydroxyapetite-collagen thereby allowing patient to retained teeth longer and at lower cost than alternative more invasive intervention like Root Canal Treatment.
研究概览
简要总结
-This is comparative evaluation of three pulp capping agent 1) Mineral trioxide aggregate (MTA) control , 2) Combination of Chitosan and Nanohydroxyapatite,3) Combination of Chitosan ,Nanohydroxyapatite and Collagen.
-Efficacy of each material checked by following criteria :
a) Quality and quantity of newly formed dentinal bridge b) Inflammatory response of pulp to Pulp capping material.
-Expected outcome :Better quality of newly formed dentinal bridge and gradual reduction in inflammatory response at 28th day and absence of pulp inflammation at 90th day will be consider as better pulp capping agent.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 15.00 Year(s) 至 25.00 Year(s)（—）
- 性别
- All
入选标准
- •Pt. between age group of 15 to 25 years will be seleted from Dept.
- •of orthodontic and dentofacial orthopedics ,bhararti vidyapeeth demeed university dental college and hospital,pune.
- •Inclusion citeria: 1) Sound permanent premolar with closed apces 2)No carious lesion 3)Normal response to pulp vitality test.
排除标准
- •Fracture teth.
结局指标
主要结局
Asymptomatic vital permanent teeth with exposed pulp can be treated successfully by direct pulp capping using combination of chitosan-nanohydroxyapetite-collagen thereby allowing patient to retained teeth longer and at lower cost than alternative more invasive intervention like Root Canal Treatment.
时间窗: sample will be assessed histopathologically under research microscope at 5th,28th and on 90th day.
次要结局
- Repair progress of pulp tissue will be assessed by checking i)dentinal bridge formation ii)inflammatory response after using different direct pulp capping material at different time interval.(1)Good dentinal bridge will formed at 28 th day)
研究者
Dr Mrunal Shinde
bharati vidyapeeth deemed to be university dental college and hospital ,pune.