MedPath

Active Elements of Digital Single-session Interventions

Not Applicable
Active, not recruiting
Conditions
Depression
Interventions
Behavioral: Psychoeducation
Behavioral: Testimonials and Saying is believing exercises
Behavioral: Action planning
Behavioral: Breathing exercise
Registration Number
NCT06322849
Lead Sponsor
Northwestern University
Brief Summary

Depression is a leading cause of disability in young adults. However, access to care is limited due to structural and psychological barriers. Single-session interventions (SSIs) are structured programs designed to maximize the therapeutic output in one interaction between the patient and the provider or a program. Project ABC, a single-session intervention (SSI), has been shown to be effective in reducing depressive symptoms. Project ABC is based on four components-psychoeducation, testimonials, saying is believing exercises, and action planning. However, it is unclear what are the effects of the individual components.

The primary aim of this study is to calculate the main effects of the candidate components-psychoeducation, testimonials + saying is believing exercises, and action planning-on Patient Health Questionnaire-8 (PHQ-8) scores at 8-week follow-up.

The secondary aims of this study are to:

1. calculate the main effects of the candidate components-psychoeducation, testimonials + saying is believing exercises, and action planning-on PHQ-8 scores at immediate post-treatment and 2-week follow-up.

2. calculate the interaction effects, if any, among the candidate components on PHQ-8 scores at immediate post-treatment, 2-week, and 8-week follow-up.

3. calculate the main and interaction effects of the candidate components on measures of hopelessness, autonomy, relatedness, and competence.

4. determine if the effects of the candidate components on PHQ-8 are mediated by measures of autonomy, relatedness, and competence.

Additionally, the exploratory aim of this study is to determine if common factors, like credibility of the intervention and expectations to improve, can lead to symptom change.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
887
Inclusion Criteria
  • Located in the United States
  • Baseline Patient Health Questionnaire-8 (PHQ-8) score >= 10
  • Able to read and write English
  • Able to access to the internet via a computer, tablet or smartphone for the next eight weeks
Exclusion Criteria
  • Participants who have participated in another related study on depression from our laboratory via the same participant recruitment platform in the past two months
  • Participants who have submitted gibberish in open response questions

Study & Design

Study Type
INTERVENTIONAL
Study Design
FACTORIAL
Arm && Interventions
GroupInterventionDescription
Arm 1PsychoeducationExperimental: Breathing exercise + active elements 1, 2, 3 In this arm, all three factors are set to active (i.e. yes): * Psychoeducation * Testimonials and Saying is believing exercises * Action planning
Arm 1Breathing exerciseExperimental: Breathing exercise + active elements 1, 2, 3 In this arm, all three factors are set to active (i.e. yes): * Psychoeducation * Testimonials and Saying is believing exercises * Action planning
Arm 4Testimonials and Saying is believing exercisesExperimental: Breathing exercise + active elements 2, 3 In this arm, two factors are set to active (i.e. yes): * Testimonials and Saying is believing exercises * Action planning
Arm 5PsychoeducationExperimental: Breathing exercise + active element 1 In this arm, one factor is set to active (i.e. yes): • Psychoeducation
Arm 7Breathing exerciseExperimental: Breathing exercise + active element 3 In this arm, one factor is set to active (i.e. yes): • Action planning
Arm 7Action planningExperimental: Breathing exercise + active element 3 In this arm, one factor is set to active (i.e. yes): • Action planning
Arm 2Testimonials and Saying is believing exercisesExperimental: Breathing exercise + active elements 1, 2 In this arm, two factors are set to active (i.e. yes): * Psychoeducation * Testimonials and Saying is believing exercises
Arm 2Breathing exerciseExperimental: Breathing exercise + active elements 1, 2 In this arm, two factors are set to active (i.e. yes): * Psychoeducation * Testimonials and Saying is believing exercises
Arm 8Breathing exerciseExperimental: Breathing exercise only In this arm, none of the three factors are set to active (i.e. yes)
Arm 1Testimonials and Saying is believing exercisesExperimental: Breathing exercise + active elements 1, 2, 3 In this arm, all three factors are set to active (i.e. yes): * Psychoeducation * Testimonials and Saying is believing exercises * Action planning
Arm 1Action planningExperimental: Breathing exercise + active elements 1, 2, 3 In this arm, all three factors are set to active (i.e. yes): * Psychoeducation * Testimonials and Saying is believing exercises * Action planning
Arm 2PsychoeducationExperimental: Breathing exercise + active elements 1, 2 In this arm, two factors are set to active (i.e. yes): * Psychoeducation * Testimonials and Saying is believing exercises
Arm 3Action planningExperimental: Breathing exercise + active elements 1, 3 In this arm, two factors are set to active (i.e. yes): * Psychoeducation * Action planning
Arm 3PsychoeducationExperimental: Breathing exercise + active elements 1, 3 In this arm, two factors are set to active (i.e. yes): * Psychoeducation * Action planning
Arm 4Breathing exerciseExperimental: Breathing exercise + active elements 2, 3 In this arm, two factors are set to active (i.e. yes): * Testimonials and Saying is believing exercises * Action planning
Arm 5Breathing exerciseExperimental: Breathing exercise + active element 1 In this arm, one factor is set to active (i.e. yes): • Psychoeducation
Arm 3Breathing exerciseExperimental: Breathing exercise + active elements 1, 3 In this arm, two factors are set to active (i.e. yes): * Psychoeducation * Action planning
Arm 6Testimonials and Saying is believing exercisesExperimental: Breathing exercise + active element 2 In this arm, one factor is set to active (i.e. yes): • Testimonials and Saying is believing exercises
Arm 6Breathing exerciseExperimental: Breathing exercise + active element 2 In this arm, one factor is set to active (i.e. yes): • Testimonials and Saying is believing exercises
Primary Outcome Measures
NameTimeMethod
Patient Health Questionnaire-8Baseline to 8-week post-intervention

Patient Health Questionnaire-8 is a well-validated and self-administered measure to assess depression symptom severity in the general population. Participants are asked to rate how often they are bothered by 8 items (e.g., Poor appetite or overeating) on a scale of 0 (Not at all) to 3 (Nearly every day). Total score can range from 0 to 24, with higher scores indicating higher symptom severity.

Secondary Outcome Measures
NameTimeMethod
Balanced measure of Psychological Needs scaleBaseline to immediate post-intervention; Baseline to 2-week post-intervention; Baseline to 8-week post-intervention

The BMPN is used as a measure of the psychological needs of autonomy, relatedness, and competence as laid out by the Self-Determination Theory. It is an 18-item questionnaire where each item is rated on a scale of 1 (Strongly disagree) to 5 (Strongly agree). Scores corresponding to each psychological need will be calculated based on the items corresponding to that need. A higher score on the three needs indicates higher wellbeing. In this study, we will use a 6-item version of the scale.

Beck Hopelessness Scale-4Baseline to immediate post-intervention; Baseline to 2-week post-intervention; Baseline to 8-week post-intervention

Beck Hopelessness Scale-4 is the 4-item version of the 20-item Beck Hopelessness scale. Participants will be asked to rate 4 items assessing different aspects of hopelessness (e.g., My future seems dark to me) on a scale of 0 (Absolutely disagree) to 3 (Absolutely agree). Total score can range between 0 to 12 with higher scores indicating higher hopelessness.

Patient Health Questionnaire-8Baseline to 2-week post-intervention

Patient Health Questionnaire-8 is a well-validated and self-administered measure to assess depression symptom severity in the general population. Participants are asked to rate how often they are bothered by 8 items (e.g., Poor appetite or overeating) on a scale of 0 (Not at all) to 3 (Nearly every day). Total score can range from 0 to 24, with higher scores indicating higher symptom severity.

Trial Locations

Locations (1)

Northwestern University

🇺🇸

Chicago, Illinois, United States

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