Indoor air quality, temperature and cognitive performance

Conditions: De cognitieve prestaties van gezonde deelnemers
thermal conditions
ventilation

Registration Number: NL-OMON56702

Lead Sponsor: Wählen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 18

Inclusion Criteria

Adults between 18 to 40 years old
Western-European background
Generally healthy
No medication which may influence the outcome parameters. This will be
determined
on a case-by-case basis. Contraceptive uses for women are allowed and will be
verified
through a questionnaire.
Non-smokers or persons who quit smoking more than five years ago

Exclusion Criteria

• Participants, who do not want to be informed about unexpected medical
findings, or do
not wish that their treating physician will be informed, cannot participate in
this study
• Individuals with a diagnosed physical or mental disability or ADHD or
depression
• Any medication or medical condition that might interfere with the
physiological outcome
parameters or in some regards impair cognition
• Unstable body weight (weight gain or loss >3kg in the past three months)
• Participation in another biomedical study within 1 month prior to screening
visit
• Shift workers
• Colour blindness
• Pregnancy
• People with a low haemoglobin or haematocrit concentration
• Not having visited or resided in a warm country in the last 3 months
• Participants with asthma or restricted lung function due to allergies

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are the achieved scores of the cognition test, mainly<br /><br>derived from the CANTAB Cognition Test and the Cognitive Ability Task.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>As secondary research objectives, it is additionally examined if humans<br /><br>perceive the air quality as less pleasant under the higher temperature, even if<br /><br>the air quality itself does not change in terms of carbon dioxide<br /><br>concentration. Also, the physiological reaction towards poor air quality and<br /><br>elevated temperature will be examined in isolation and interaction.<br /><br>Specifically, it will be investigated how these two factors affect the<br /><br>following physiological parameters: Capillary blood CO2 and pH level, salivary<br /><br>cortisol and alpha-amylase, blood cytokins serum concentration, lung function,<br /><br>heart rate, respiration rate, skin temperature, core temperature, blood<br /><br>pressure, physical activity, and metabolic rate.</p><br>