HMB on muscle function in OA with THA or TKA

Not Applicable

Recruiting

• Conditions: osteoarthritis; osteoarthritis, osteoarthritis of the hip, osteoarthritis of the knee; D010003

• Registration Number: JPRN-jRCTs051200094
• Lead Sponsor: yasuda tadashi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-12-11
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

1)Patients with osteoarthritis who undergo total hip or knee arthroplasty
2)Patients who will be able to receive standard postoperative rehabilitation
3)Patients who will be able to receive regular follow-up
4)Female patients at age 65 and more at the time of consent acquisition
5)Patients who have voluntarily consented to participate in this study with their comprehension on thorough explanation of this study

Exclusion Criteria

1)Patients who had taken HMB before consent acquisition
2)Patients who had taken medicine or supplement that may affect muscle function
3) Patients who are not expected to receive the standard recovery rehabilitation at the recovery phase hospital after transfer from our hospital
4)Patients with radiotherapy or chemotherapy, or with treatment with steroid or immunosuppressive drugs
5)Patients with paresis
6)Patients with history of malignancy within the last 5 years
7)Patients with history of unstable angina, cardiac infarction, brain infarction, cerebral hemorrhage, or transient cerebral ischemic attack within the last 6 months
8)Patients with severe diseases in liver, kidney, heart, lung, blood, or endocrine and metabolic systems
9)Patients with or with history of inflammatory joint diseases except osteoarthritis
10)Patients with history of total hip or knee arthroplasty within the last 6 months
11)Patients under consideration of other surgical treatment during the protocol period of this study
12)Patients participating in other interventional or clinical trial
13)Patients who are considered inappropriate as the subjects for this study by the principal investigator or co-investigators

Study & Design

• Study Type: Interventional
• Study Design: Not specified