Comparison of High Frequency Jet Ventilation and Conventional Positive Pressure Ventilation for Endobronchial Ultrasound Examinations
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 428
- 试验地点
- 1
- 主要终点
- Hemodynamic instability
研究概览
简要总结
Endobronchial ultrasound (EBUS) is frequently used in pneumology for diagnostic procedures like mediastinal biopsies. This procedure is usually done under general anesthesia. Different methods of ventilation are used according to center and physician preferences. In this retrospective study, complications of 2 types of ventilation will be analyzed:
- High frequency jet ventilation (HFJV)
- Conventional intermittent positive pressure ventilation (IPPV) Descriptive statistics will be used to present the data. Both ventilation techniques will be compared after propensity score matching. For HFJV patients from 2019 will be analyzed and for IPPV patients from 2023, as the team changed its practice over time.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients who underwent EBUS at Erasme University Hospital using either HFJV or IPPV between january 1st 2019 and december 31st 2019 or january 1st 2023 and december 31st 2023.
排除标准
- •Incomplete medical chart
- •Patients who expressed an opposition to the use of their medical data
- •Age < 18 years
结局指标
主要结局
Hemodynamic instability
时间窗: 24 hours
defined as a systolic arterial blood pressure \< 90/60 mm Hg
Cardiac arrythmia
时间窗: 24 hours
Any cardiac rhythm other than sinus rhythm
Hypoxia
时间窗: 24 hours
defined as an SpO2 \< 90% for more than 1 min
Severe hypoxia
时间窗: 24 hours
defined as an SpO2 (oxygen saturation by pulse oximetry) \< 85% for more than 1 min
Laryngospasm
时间窗: 24 hours
Any occurence of laryngospasm
ICU admission
时间窗: 24 hours
Necessity for admission to the intensive care unit (ICU)
次要结局
未报告次要终点