Influence of Lower Extremity Muscles Strength on Physical Function, Biomechanical Gait Parameters and Reported Outcome After Total Knee Arthroplasty
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Gait biomechanics analysis - step length
研究概览
简要总结
Total Knee Arthroplasty (TKA) is actually the most effective treatment option for patients with end-stage osteoarthritis (OA). However, nearly 20% of patients who underwent TKA remain unsatisfied with their clinical outcome. Investigating modifiable factors that limit knee functioning following TKA we may notice the significance of lower limb muscles strength. Gait pattern is also affected by OA, as arthritic knee joint cannot provide proper range of motion (ROM) and stability.Therefore any deviation in biomechanics should be noticed and analyzed. After TKA patients' physical function may change, but the study should be conducted to prove whether it improves or not. Patient-reported outcome defined by OKS (Oxford Knee Score) and FJS (Forgotten Joint Score) questionnaires will be evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •III° or IV° grade knee osteoarthritis
- •Age over 50
- •Patients with signed consent
排除标准
- •Undergone total hip replacement
- •Previous femur fracture in anamnesis
- •Undergone corrective osteotomy
- •Active/ Chronic neoplastic disease
- •Significant deformation of lower limb axis
- •Mental disorders
- •Muscular disorders
结局指标
主要结局
Gait biomechanics analysis - step length
时间窗: 6 months
Analysis of pre- and postoperative parameters of gait pattern and biomechanics with a use of Baiobit device (wearable motion analysis system). Subjected to the analysis will be the step length (in meters).
Muscle strength measurement with a use of dynamometer
时间窗: 6 months
Analysis of pre- and postoperative strength of lower limb muscles. Assessment of force \[N\] generated by knee flexors, knee extensors, hip adductors and hip abductors with a use of a hand-held dynamometer.
Gait biomechanics analysis - gait speed
时间窗: 6 months
Analysis of pre- and postoperative parameters of gait pattern and biomechanics with a use of Baiobit device (wearable motion analysis system). Subjected to the analysis will be the gait speed (metre per second).
Gait biomechanics analysis - phases of gait
时间窗: 6 months
Analysis of pre- and postoperative parameters of gait pattern and biomechanics with a use of Baiobit device (wearable motion analysis system). Subjected to the analysis will be the swing and the stance phase of gait (% of the gait cycle).
Gait biomechanics analysis - step duration
时间窗: 6 months
Analysis of pre- and postoperative parameters of gait pattern and biomechanics with a use of Baiobit device (wearable motion analysis system). Subjected to the analysis will be the duration of left and right step (in seconds).
Physical function assessment based on standardized test
时间窗: 6 months
Analysis of pre- and postoperative physical function on the basis of Up and Go test.
次要结局
- Patient-reported outcome - Oxford Knee Score(6 months)
- Patient-reported outcome - Forgotten Joint Score(6 months)
研究者
Artur Stolarczyk
Professor
Medical University of Warsaw