Evaluation of Treatments for Homeless Youths

Phase 2

Completed

Conditions: Substance Abuse

Interventions: Behavioral: Community Reinforcement Approach (CRA) + HIV prevention
Behavioral: Case Management + HIV Prevention
Behavioral: Motivational Enhancement Therapy (MET) + HIV prevention

Registration Number: NCT01143792

Lead Sponsor: Ohio State University

Brief Summary: Youth who leave home for the streets are at significantly more risk for a multitude of problems, yet little research is available to guide treatment intervention efforts with this population. Studies document high rates of substance use, HIV risk, mental health problems, teenage pregnancy and criminality. Research to date examining homeless, street living youth has been primarily descriptive; less effort has been directed towards developing and evaluating treatment interventions for this group. The majority of homeless youth do not receive substance abuse treatment, with one study reporting that only 15% of street living youth report ever receiving mental health services. The effectiveness of the Community Reinforcement Approach (CRA) with street living youth was studied in our recently completed Stage 1 trial. The proposed study is a Stage II clinical trial examining outcome of CRA individual therapy as compared to two interventions commonly employed, yet little researched, with this group. All clients will be randomized to one of three theoretically distinct interventions: (1) CRA therapy, (2) Motivational Enhancement Therapy (MET), or (3) Case Management (CM). The relative effectiveness of these interventions will be evaluated at 3, 6, and 12 months post-baseline. The Social Ecology Theory of Development (Bronfenbrenner, 1979) guides our change hypotheses and intervention. Proposed change mechanisms (mediators) for each intervention will be evaluated. Differential treatment response as a function of ethnicity, gender, age, sexual orientation and abuse (moderators) will be investigated to better understand the interventions. The study will also examine how, if at all, treatment engagement, retention and expectations impact youth response to the three treatments. Information gained through this project may help address the gap in our understanding of how best to effectively intervene with a group at high risk for continuing health and psychological problems.

Detailed Description: Not available

Recruitment & Eligibility

Status: COMPLETED

Sex: All

Target Recruitment: 270

Inclusion Criteria

Youth are between the ages of 14-20.
Youth have plans to remain in the Columbus areas for at least 12 months.
Youth meets abuse or dependence DSM-IV criteria for Psychoactive Substance Use or Alcohol disorder, as assessed by the computerized diagnostic interview schedule for children (CDISC, Shaffer, 1992).
Youth agrees to participate in the assessment and treatment intervention.
Youth meets criteria for homelessness as defined by DHHS.

Exclusion Criteria

Evidence of unremitted psychosis or other condition which would impair their ability to understand and participate in the intervention or consent for research participation (as determined by CDISC).

Study & Design

Study Type: INTERVENTIONAL

Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CRA + HIV prevention	Community Reinforcement Approach (CRA) + HIV prevention	-
Case Management + HIV prevention	Case Management + HIV Prevention	-
MET + HIV prevention	Motivational Enhancement Therapy (MET) + HIV prevention	-

Primary Outcome Measures

Name	Time	Method
Substance Use	Twelve months	Percentage of substance use days in prior six months

Secondary Outcome Measures

Name	Time	Method
HIV Risk	Twelve months	Frequency of condoms use in prior six months.
Depressive Symptoms	Twelve months	Beck Depression Inventory - II (BDI-II) total score, range from 0 (no depression)to 63 (severe depression)