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临床试验/NCT01143792
NCT01143792已完成2 期

Evaluation of Treatments for Homeless Youth: CRA, MET and Case Management

Ohio State University2 个研究点 分布在 1 个国家目标入组 270 人开始时间: 2006年9月最近更新:
适应症

试验速览

阶段
2 期
状态
已完成
入组人数
270
试验地点
2
主要终点
Substance Use

研究概览

简要总结

Youth who leave home for the streets are at significantly more risk for a multitude of problems, yet little research is available to guide treatment intervention efforts with this population. Studies document high rates of substance use, HIV risk, mental health problems, teenage pregnancy and criminality. Research to date examining homeless, street living youth has been primarily descriptive; less effort has been directed towards developing and evaluating treatment interventions for this group. The majority of homeless youth do not receive substance abuse treatment, with one study reporting that only 15% of street living youth report ever receiving mental health services. The effectiveness of the Community Reinforcement Approach (CRA) with street living youth was studied in our recently completed Stage 1 trial. The proposed study is a Stage II clinical trial examining outcome of CRA individual therapy as compared to two interventions commonly employed, yet little researched, with this group. All clients will be randomized to one of three theoretically distinct interventions: (1) CRA therapy, (2) Motivational Enhancement Therapy (MET), or (3) Case Management (CM). The relative effectiveness of these interventions will be evaluated at 3, 6, and 12 months post-baseline. The Social Ecology Theory of Development (Bronfenbrenner, 1979) guides our change hypotheses and intervention. Proposed change mechanisms (mediators) for each intervention will be evaluated. Differential treatment response as a function of ethnicity, gender, age, sexual orientation and abuse (moderators) will be investigated to better understand the interventions. The study will also examine how, if at all, treatment engagement, retention and expectations impact youth response to the three treatments. Information gained through this project may help address the gap in our understanding of how best to effectively intervene with a group at high risk for continuing health and psychological problems.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
14 Years 至 20 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Youth are between the ages of 14-
  • Youth have plans to remain in the Columbus areas for at least 12 months.
  • Youth meets abuse or dependence DSM-IV criteria for Psychoactive Substance Use or Alcohol disorder, as assessed by the computerized diagnostic interview schedule for children (CDISC, Shaffer, 1992).
  • Youth agrees to participate in the assessment and treatment intervention.
  • Youth meets criteria for homelessness as defined by DHHS.

排除标准

  • Evidence of unremitted psychosis or other condition which would impair their ability to understand and participate in the intervention or consent for research participation (as determined by CDISC).

结局指标

主要结局

Substance Use

时间窗: Twelve months

Percentage of substance use days in prior six months

次要结局

  • HIV Risk(Twelve months)
  • Depressive Symptoms(Twelve months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Natasha Slesnick

Ph.D.

Ohio State University

研究点 (2)

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