A study comparing the efficacy and tolerability of Co-amoxiclav,Cefpodoxime and Levofloxacin in tonsillitis
- Conditions
- Health Condition 1: null- Acute, uncomplicated bacterial tonsillitis
- Registration Number
- CTRI/2018/05/013756
- Lead Sponsor
- Kempegowda Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
•Subjects of either gender between 10 - 55 years diagnosed as acute bacterial tonsillitis as confirmed by throat swab.
•Willingness to give written informed consent and availability for regular scheduled follow up.
•Subjects with suspected viral tonsillitis.
•Subjects with complications like quinsy, parapharyngeal abscess, AOM, suppurative cervical adenitis.
•Subjects with coexisting LRTIs / sinusitis
•Patients with severe renal and/or hepatic dysfunction
• Pregnant and lactating women
• Those who had taken antibiotics within the previous 48 hours or those who had received long acting penicillins within 2 weeks before enrolment into the study.
•Subjects with history of any hypersensitivity/or any SAE, to any of the study medications.
•Immunocompromised subjects, and in the presence of disorders associated with muscle weakness.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of Co-amoxiclav,Cefpodoxime proxetil and levofloxacin in acute ,uncomplicated bacterial tonsillitisTimepoint: 18 months
- Secondary Outcome Measures
Name Time Method To assess the tolerability of study medicationsTimepoint: 18 months