Evaluation of an exercise treatment strategy in patients with knee osteoarthritis and comorbidity (COOA): Randomized Clinical Trial - Comorbidity and exercise therapy in patients with knee osteoarthritis: RCT

Koningklijk Nederlands Genootschap Fysiotherapie0 个研究点目标入组 154 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•- diagnoses of knee OA according to the clinical ACR criteria, i.e: knee pain and at least three of the following six: age > 50 years, morning stifness <30 minutes, crepitus, bony tenderness, bony enlargement and no palpable warmth
•- at least one of the following comorbidities (diagosed by a physican), with a score *2 on the Cumulative Illness Rating Scale (ie the comorbidity has influence on daily functioning and treatment of the comorbifity is necessary): coronary heart diseases, heart failure, diabetic type 2, obesity, chronic obstructive pulmonary diseases (COPD)
•- focus of treatment is on OA- related diability (instead of comorbidity -related disability)

•- absolute contraindication for exercise therapy
•- indication of knee prothesis
•- refusal to sign informed consent
•- insufficient control over the Dutch language
•- patients with a high score of psychological distress (HADS score>11, SCL-90 score >150)
•- dementia (MMSE score >26)
•- suffering from significant physical limitations (possibly caused by co-morbidities) that would prohibit a patient from following the physiotherapy program.
•- Patients who are expected to be lost for follow-up (e.g. because of a planned change of residency

发起方

Koningklijk Nederlands Genootschap Fysiotherapie