Incidence, Treatment of and Outcome of Acute Mesenteric Ischemia in the Region of Västra Götaland, 2000-2023 - a Retrospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 2,446
- 试验地点
- 2
- 主要终点
- Incidence of acute mesenteric ischemia
研究概览
简要总结
The goal of this retrospective observational study is to describe the incidence and outcome of patients diagnosed with acute mesenteric ischemia (AMI) in the Västra Götaland region of Sweden between 2000-2023. The main questions it aims to answer are:
- What was the observed incidence and outcome, and how did it change during the time period?
- How did socioeconomic factors influence incidence and outcome of AMI?
- What main surgical approaches were selected for these patients?
- What was the distribution of anticoagulant use in the cohort, and what effect did the introduction of new oral anticoagulants (NOAC) have on incidence and mortality in AMI?
- What was the prevalence of Short Bowel Syndrome (SBS) after surgical intervention?
Participants were obtained from the regional diagnosis registry. Additional datapoints were obtained from the Swedish statistics bureau and pharmaceutical registers.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients discharged from hospital with acute mesenteric ischemia (ICD K55.0 and K55.9)
排除标准
- 未提供
结局指标
主要结局
Incidence of acute mesenteric ischemia
时间窗: Year 2000-2023
Annual incidence rate of acute mesenteric ischemia per 100,000 person-years in the Västra Götaland region.
Mortality from acute mesenteric ischemia
时间窗: 30 days, 90 days, 1 year.
All-cause mortality within up to 1 year of AMI diagnosis.
次要结局
- Temporal trends in incidence and mortality(Year 2000-2023)
- Socioeconomic determinants of incidence and outcome(Year 2000-2023)
- Surgical management strategy(Year 2000-2023)
- Prevalence of Short Bowel Syndrome (SBS)(Within 1 year of surgical intervention)
- Anticoagulant use patterns(At AMI diagnosis; trends from 2000-2023)
研究者
Hanna de la Croix
MD, PhD
Sahlgrenska University Hospital