To evaluate the efficacy of Haridradwaya Churna with and without Vamana Karma in the management of Sthaulya w.s.r. to Dyslipidemia- A randomised comparative clinical study.

INTRODUCTION-

Dyslipidemia is a disorder of lipoprotein metabolism which can include overproduction or deficiency of lipoprotein or both. The disorder can manifest as an elevation of plasma cholesterol ,triglyceride or both or a low level of high density lipoprotein or all three together that contributes to the development of atherosclerosis. As Dyslipidemia is metabolic disorder, It requires long term treatment and drug like statins are the first choice in the treatment of Dyslipidemia. The data from the US National Health and Nutrition Examination Survey conducted from 1999 to 2000 reported that 25% of adults either had total cholesterol >239.4 mg/dl or were taking a lipid-lowering medication. Lifestyle modifications should always be a part of the management of dyslipidemia. However, the need for long-term, lifelong therapy is associated with several adverse effects such as myopathy, increased risk of renal failure, hypothyroidism and memory loss in 15%-20% of the patients on treatment with statins. But the holistic approach of Ayurveda treatments seems to be safe and cost effective as it targets the route cause of the disease particularly by use of Panchakarma and natural medicine like herbs, hence the present study is planned.

 OBJECTIVES –

PRIMARY:

1. To evaluate the efficacy of Vamana karma with Vatsak beeja choorna + Madana phala pippali choorna and Kovidar kashaya .

2. To compare the efficacy of Haridradwaya choorna with and without Vamana Karma in management of Sthoulya (dyslipidemia).

 SECONDARY:

Reduction in symptoms of sthoulya like –

Kshudhaadhikya

pipasa aadhikya

Gatradourgandhya

Chala sphik-udara-stana

Angagaurava

Nidradhikya Gatra sadana

Javoparodha

Reduction in level of pathological parameter of Dyslipidemia viz. serum cholesterol, serum Triglycerides, serum HDL, serum LDL, serum VLDL .

 METHODOLOGY:

STUDY TYPE – Interventional

INTERVENTION METHOD – Parallel

TIME PERSPECTIVE – Prospective

MASKING - Open Label

SAMPLE SIZE- 30

GROUPING - Two groups, Group A (15) & Group B(15).

Duration- 30 days

Followup- 31st days