The Development of Artificial Intelligence Dry Eye Screening and Referral System
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 1,273
- Locations
- 1
- Primary Endpoint
- Area under the curve (severe)
Study Overview
Brief Summary
Dry eye is one of the most common ocular surface diseases. Its pathogenic factors are related to multiple etiology. Because of the complexity of the pathogenesis of dry eye, the diversity of related examinations, and the inconsistency of symptoms and signs of dry eye patients, the diagnosis of dry eye has higher requirements on the professional technology and examination equipment of ophthalmologists.
The purpose of this study is to establish a case-control cohort of dry eye patients. Multimodal data will be collected from participants, including medical history information, ocular surface disease index scale (OSDI), anterior segment photography, and treatment outcome of dry eye patients. The correlation between the characteristics of anterior segment images and dry eye diagnosis will be explored by artificial intelligence algorithms. The purpose of this study was to develop an artificial intelligence dry eye screening and referral system.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Subjects whose age are greater than or equal to 18 years old;
- •Subjects who can cooperate with the inspection;
- •Subjects who agree to participate in the study and sign the consent form.
Exclusion Criteria
- •Subjects who cannot do the inspection.
- •Subjects who suffer from diseases that compromise the inspection.
Arms & Interventions
Mild group
This group of subjects was diagnosed with dry eye but can use artificial tears instead of further treatment.
Intervention: Dry eye diagnostic test (Diagnostic Test)
Follow-up group
This group of subjects had no dry eye symptoms and signs and belonged to the normal control group.
Intervention: Dry eye diagnostic test (Diagnostic Test)
Severe Group
This group of subjects needed a referral to the hospital for further treatments.
Intervention: Dry eye diagnostic test (Diagnostic Test)
Outcomes
Primary Outcomes
Area under the curve (severe)
Time Frame: up to 1 month
AUC values for predicting whether subject need to be referral or not.
Secondary Outcomes
- Area under the curve (each group)(up to 1 month)
- Accuracy, true positive rate, and true negative rate(up to 1 month)
Investigators
Haotian Lin
Professor
Sun Yat-sen University