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Clinical Trials/NCT04413370
NCT04413370
Unknown
Not Applicable

The Development of Artificial Intelligence Dry Eye Screening and Referral System

Sun Yat-sen University1 site in 1 country518 target enrollmentJanuary 6, 2020
ConditionsDry Eye

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dry Eye
Sponsor
Sun Yat-sen University
Enrollment
518
Locations
1
Primary Endpoint
Area under the curve (severe)
Last Updated
4 years ago

Overview

Brief Summary

Dry eye is one of the most common ocular surface diseases. Its pathogenic factors are related to multiple etiology. Because of the complexity of the pathogenesis of dry eye, the diversity of related examinations, and the inconsistency of symptoms and signs of dry eye patients, the diagnosis of dry eye has higher requirements on the professional technology and examination equipment of ophthalmologists.

The purpose of this study is to establish a case-control cohort of dry eye patients. Multimodal data will be collected from participants, including medical history information, ocular surface disease index scale (OSDI), anterior segment photography, and treatment outcome of dry eye patients. The correlation between the characteristics of anterior segment images and dry eye diagnosis will be explored by artificial intelligence algorithms. The purpose of this study was to develop an artificial intelligence dry eye screening and referral system.

Registry
clinicaltrials.gov
Start Date
January 6, 2020
End Date
August 1, 2022
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Sun Yat-sen University
Responsible Party
Principal Investigator
Principal Investigator

Haotian Lin

Professor

Sun Yat-sen University

Eligibility Criteria

Inclusion Criteria

  • Subjects whose age are greater than or equal to 18 years old;
  • Subjects who can cooperate with the inspection;
  • Subjects who agree to participate in the study and sign the consent form.

Exclusion Criteria

  • Subjects who cannot do the inspection.
  • Subjects who suffer from diseases that compromise the inspection.

Outcomes

Primary Outcomes

Area under the curve (severe)

Time Frame: up to 1 month

AUC values for predicting whether subject need to be referral or not.

Secondary Outcomes

  • Area under the curve (each group)(up to 1 month)
  • Accuracy, true positive rate, and true negative rate(up to 1 month)

Study Sites (1)

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