A clinical trial to evaluate the efficacy of Vayasthapana Compound in the management of Akalaja Jara w.s.r to Premature Ageing
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Improvement in sign and symptoms of Akalaja Jara
研究概览
简要总结
Ageing is a universal process that began with the origin of life. It is defined as the process of growing old, damage to cells, tissues and organs with the passage of time. It is a complex, systemic physiological process characterized by progressive degradation, loss of function, and reduced repair capacity of tissues, cells, organ and make us more susceptible to death. Chronological aging is an irreversible process but the factors causing biological aging can be controlled. We have chosen the drugs of Vayasthapan mahakashaya as mentioned in Charaka Samhita Sutrasthan chapter 4. In classics, it is mentioned that Vayasthapana drugs improves the quality of life, memory, youthfulness and brightness etc. It prevents ill health and block geriatric symptoms. This study is designed to identify the effect of Compund drugs from Vayasthapana mahakashaya to improve the sign and symptoms of Premature Ageing. A clinical study will be conducted to see the efficacy of Vayasthapana Compound churna in improving the signs and symptoms of Akalaja Jara (Premature Ageing). At first, all participants will be screened to check their eligibility for the study. A total of 60 clinically diagnosed patients will be enrolled in this study after taking informed written consent. After that, the first assessment will be done before drug administration with a validated questionnaire and grading will be done according to the signs and symptoms of the patients. Then the drug therapy will be started and the total duration will be 90 days. Three follow ups will be done each after 30 days. The last assessment will be done on the 90th day and the grading will be given again to see the changes in the signs and symptoms of Akalaja Jara . Signatures on informed consent and patient information sheets will be taken on hard copy, and all other relevant data for the study will be collected. After the collection of all the relevant data, the analysis of the data will be done.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 31.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients between age of 31 to 50 years of age with clinical features of Akalaja Jara(Premature ageing) 2.Patients of either sex,irrespective of their caste,religion etc.
- •3.Patient willing to give informed consent to participate in trial.
排除标准
- •1.Patient less than 31 years and more than 50 years of age 2.Patients diagnosed with any major diseases like carcinoma.
- •3.Patients with any chronic disease or Dhatukshayatva involved in the pathophysiology of disease like Madhumeha, Rajyakshama.
- •4.Patients diagnosed with any systemic disorders like cardiovascular disorders, hepatic disorders, renal disorders and cerebrovascular disorders.
- •5.Pregnant and lactating mothers.
- •6.Females in Perimenopausal phase having symptoms like irregular menstruation, flashes and night sweats etc.
- •7.Patient had completed participation in any other clinical trial in past 6 months.
结局指标
主要结局
Improvement in sign and symptoms of Akalaja Jara
时间窗: 90 days
次要结局
- 1.Improvement in quality of life(2.Time taken to walk a distance of 10 metres.)
研究者
Dr Muskan
KSVAMC RC Gangoh