Short term effects of herbal tea on mood, cognition and metabolic performance

Not Applicable

• Conditions: cognition; metabolic syndrome; mood; Alternative and Complementary Medicine - Herbal remedies; Metabolic and Endocrine - Metabolic disorders; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12616000432415
• Lead Sponsor: Professor Marc Cohen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-04-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Group 1-Healthy volunteers
-Non-smoker
-Age between 18 and 60 years
- English speaking
-Healthy (absence of all exclusion criteria) male and female adults
- Not taking any medication, herbal extracts, vitamin supplements or illicit drugs
- Participants must avoid caffeine-containing drinks and alcohol for 24 hours prior to the testing sessions
- Written informed consent

Group2- Elite Athletes
Non-smoker
- Elite athlete participating at competition level team sports
-Age between 18 and 60 years
- English speaking
-Healthy (absence of all exclusion criteria) male and female adults
- Not taking any medication, herbal extracts, vitamin supplements or illicit drugs
- Participants must avoid caffeine-containing drinks and alcohol for 24 hours prior to the testing sessions
- Written informed consent

Group 3-impaired glucose individuals
Non-smoker
-consist of people with impaired glucose control as defined by Fasting Blood Glucose between 5.5 - 6.9mmol/L or Random Blood Glucose between 5.5-11 mmol/L
-Age between 18 and 60 years
- English speaking
-Healthy (absence of all exclusion criteria) male and female adults
- Not taking any medication, herbal extracts, vitamin supplements or illicit drugs
- Participants must avoid caffeine-containing drinks and alcohol for 24 hours prior to the testing sessions
- Written informed consent

Exclusion Criteria

- Smokers
-Taking herbal extracts, vitamin supplements or illicit drugs
-diagnosed with diabetes
-chronic infection or illness
-Current or previous history of cardiac, gastrointestinal, liver or psychiatric disorders
- regular consumption of Tulsi tea
- Reported participation in another related trial within three months or during this study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive Function assessed using CogState computerized battery[at baseline, after 60minutes following treatment (T60)]

Secondary Outcome Measures

Name	Time	Method
blood pressure measured by an oscillometric device[baseline, at 1 hour (T1), 2 hours (T2) and 4 hours (T4)];Measurement of the Mood states using a Profile of Mood States (POMS) questionnaire consisting of 65-adjectives that participants will rate on a 5-point scale. <br><br>The 1-5 Likert scale (1 being not at all” and 5 being extremely) will be used for Participants to rate the level at which they have been feeling during the study.[test will be conducted at base line and at 1 hour post intervention];Aerobic Capacity testing (VO2). This outcome will be measured using beep test<br>[measured only 30 minutes after intervention (T30)];fasting blood glucose levels[measured at baseline and after 60minutes post intervention];RNA transcriptome analysis of blood samples[at baseline and after 60minutes post intervention]