Conservative treatment of Ectopic Pregnancy in Cesarean Scar with Local Injection of Methotrexate guided by Transvaginal Ultrasonography versus Chemoembolization via Utterine Artery: a prospective randomized multicentric study

Escola Paulista de Medicina da Universidade Federal de São Paulo0 个研究点开始时间: 2024年6月26日最近更新: 2024年7月22日

适应症

试验速览

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•18 years of age or older; Hemodynamic stability, defined as diastolic blood pressure greater than or equal to 60 mmHg and systolic blood pressure greater than or equal to 90 mmHg, heart rate less than 100 bpm, and capillary refill time less than or equal to 3 seconds; Gestational age less than 12 weeks; Intact gestational sac in topography of the cesarean scar with embryo with heartbeat; Absence of signs of peritonism; Pregnancy in the exogenous cesarean section scar (COS-1); Myometrial mantle less than 5mm; Desire for a future pregnancy or not wanting to have a hysterectomy; Ease of returning to the hospital if necessary; Signed consent form

•Hemoglobin less than 10 g/dl; Leukopenia (leukocytes less than 2,000 cells/mm3); Thrombocytopenia (platelets less than 100,000/mm3); Immunodeficiency, defined by the use of immunosuppressive drugs such as corticoids; Allergy to methotrexate; Current chronic lung disease, such as chronic obstructive pulmonary disease; Liver transaminases above the maximum reference value; Creatinine above the maximum reference value; Breastfeeding; Refusal to receive blood transfusion; Inability to continue the follow-up

发起方

Escola Paulista de Medicina da Universidade Federal de São Paulo