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Panc dose escalatio

Phase 1
Recruiting
Conditions
pancreatic cancer
Registration Number
JPRN-jRCTs032210292
Lead Sponsor
Yamada Shigeru
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
24
Inclusion Criteria

(1) Histologically or clinically diagnosed primary pancreatic tumor
(2) No indication for curative resection or no desire for surgery
(3) Has evaluable disease
(4) No obvious distant metastasis
(5) Age at the time of enrollment is 20 years or older
(6) Have a performance status (EGOG) of 0-2
(7) No prior surgical resection*1 or radiation therapy for pancreatic cancer
*1: Excluding simple laparotomy, gastrojejunostomy, and bile duct jejunal anastomosis
(8) Patients who are estimated to have a chance of survival for at least 3 months
(9) Patient's written consent for participation in the study has been obtained.

Exclusion Criteria

(1) Tumor involvement in the mucosal surface of the gastrointestinal tract
(2) A metal stent has been inserted.
(3) Active gastroduodenal ulcer is present
(4) Active and refractory infection in the irradiated area
(5) Patient has serious complications
(6) History of radiation therapy in the area
(7) It is judged that it is difficult to carry out this study for medical, psychological, or other reasons. Other reasons that the physician deems inappropriate for enrollment in this study
(8) Adult who lacks the capacity to give consent
(9) Eligible for the clinical trial of [A clinical trial for efficacy and safety on carbon-ion radiotherapy and concurrent GEM chemotherapy for locally advanced pancreatic cancer] (jRCT1031190131)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Acute adverse reactions
Secondary Outcome Measures
NameTimeMethod
ate adverse reactions, local control rate, overall survival period
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