Effectiveness of Dhanyavilwadhi Kashaya and Nagarapippalyadhi Kashaya in the Management of Irritable Bowel syndrome - A Comparative Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- ROME Criteria-based improvement
研究概览
简要总结
The prevalence of IBS ranges from 10% to 15% worldwide, making it a major health concern. The condition leads to chronic symptoms which significantly impact patients’ quality of life and daily functioning. Women are two to four times more likely to develop IBS than men. Age-related onset of IBS symptoms occurred predominantly in patients younger than 45 years, but prevalence rose again in the elderly. The development of symptoms in people older than 40 years does not exclude IBS but should prompt a closer search for an underlying organic etiology. The prevalence varies according to country and criteria used to define IBS. Allopathic treatments have limited success in curing Grahani disease, and patients often experience significant complications. Effective management strategies are essential to alleviate these symptoms and enhance patient well-being. So, this study will compare the effectiveness of Dhanyavilwadi Kashaya and Nagarapippalyadi Kashaya in managing irritable bowel syndrome (IBS) symptoms.
This research is vital for improving treatments for irritable bowel syndrome (IBS), which significantly impacts daily life. Conventional therapies often provide inadequate relief and can have side effects, creating a need for effective alternatives.
Dhanyavilwadi Kashaya and Nagarapippalyadi Kashaya are Ayurvedic formulations that promote digestive health and dosha balance. However, scientific evidence supporting their efficacy is limited. This study aims to provide empirical data on their effectiveness.
Null Hypothesis:
There is no significant difference in the efficacy of Dhanyavilwadi Kashaya and Nagarapippalyadi Kashaya in the management of irritable bowel syndrome.
Alternative Hypothesis
There is a significant difference in the effectiveness of Dhanyavilwadi Kashaya significantly more effective than Nagarapippalyadi Kashaya in the management of irritable bowel syndrome
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Subjects who have signed the informed consent 2 Patients having symptoms of IBS diagnosed based on Rome criteria.
排除标准
- •Patients having an age that is less than 18 and greater than 60 years Patients suffering from Acute diarrhoea Intestinal TB Ulcerative colitis Gastric and Peptic ulcers Diabetes and Chronic kidney disorder Hyperthyroidism Malignancies Amoebic dysentery.
结局指标
主要结局
ROME Criteria-based improvement
时间窗: 0th day | 15th day | 30th day | 45th day
次要结局
- ROME Criteria-based improvement(Change in individual symptom severity)
研究者
Dr Suresh V S
Glocal College of Ayurvedic Medical Science and Research Centre