Efficacy of Different Doses of Dexmetomedine as an Adjuvant to Bupivacaine in Ultrasound Guided PECS Block in Patients Undergoing Modified Radical Mastectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 96
- 试验地点
- 2
- 主要终点
- postoperative pain
研究概览
简要总结
Regional anesthesia is an essential component of anesthesia and analgesia. It has many advantages, it decreases pain post operatively, improves patient outcome and allow early recovery and ambulation Post-operative pain following breast surgery results from injured muscles and nerves, management of acute post operative pain is a consistent factor for better outcome and patient satisfaction
详细描述
All patients will be monitored by standard intraoperative monitoring that includes continuous electrocardiography (ECG), capnography, pulse oximetry, and non invasive blood pressure.
Induction of general anesthesia will be done by propofol 1.5-2 mg/kg and fentanyl 3µg/kg.
Tracheal intubation will be facilitated by administration of rocuronium 0.8 mg/kg. Anesthesia will be maintained with isoflurane 1MAC (Pecs block):the block will be performed with the patients in the supine position.The infraclavicular and axillary regions will be cleaned with antiseptic solution. the in plane technique will be used from proximal and medial to distal and lateral in an oblique manner at dermatome level T2 and T3.The puncture site was infiltrated with 2%lidocaine and once the structures is identified with Ultrasound
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •adult patients
- •aged 18-60years old
- •ASA class 1 to 3
- •scheduled for elective modified radical mastectomy
排除标准
- •patients refusal,
- •coagulopathies
- •concurrent anticoagulant therapy
- •allergy to local anaesthetics
- •infection at puncture site
结局指标
主要结局
postoperative pain
时间窗: 48 hours
Visual analog score for pain where 0 no pain and 10 most severe pain
次要结局
- Total morphine consumption(48 hours)
研究者
rabab Mohammad habeeb
Principal investigator
Menoufia University