Efficacy of Different Doses of Dexmetomedine as an Adjuvant to Bupivacaine in Ultrasound Guided PECS Block in Patients Undergoing Modified Radical Mastectomy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Post Operative Pain
- Sponsor
- Menoufia University
- Enrollment
- 96
- Locations
- 1
- Primary Endpoint
- postoperative pain
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Regional anesthesia is an essential component of anesthesia and analgesia. It has many advantages, it decreases pain post operatively, improves patient outcome and allow early recovery and ambulation Post-operative pain following breast surgery results from injured muscles and nerves, management of acute post operative pain is a consistent factor for better outcome and patient satisfaction
Detailed Description
All patients will be monitored by standard intraoperative monitoring that includes continuous electrocardiography (ECG), capnography, pulse oximetry, and non invasive blood pressure. Induction of general anesthesia will be done by propofol 1.5-2 mg/kg and fentanyl 3µg/kg. Tracheal intubation will be facilitated by administration of rocuronium 0.8 mg/kg. Anesthesia will be maintained with isoflurane 1MAC (Pecs block):the block will be performed with the patients in the supine position.The infraclavicular and axillary regions will be cleaned with antiseptic solution. the in plane technique will be used from proximal and medial to distal and lateral in an oblique manner at dermatome level T2 and T3.The puncture site was infiltrated with 2%lidocaine and once the structures is identified with Ultrasound
Investigators
rabab Mohammad habeeb
Principal investigator
Menoufia University
Eligibility Criteria
Inclusion Criteria
- •adult patients
- •aged 18-60years old
- •ASA class 1 to 3
- •scheduled for elective modified radical mastectomy
Exclusion Criteria
- •patients refusal,
- •coagulopathies
- •concurrent anticoagulant therapy
- •allergy to local anaesthetics
- •infection at puncture site
Outcomes
Primary Outcomes
postoperative pain
Time Frame: 48 hours
Visual analog score for pain where 0 no pain and 10 most severe pain
Secondary Outcomes
- Total morphine consumption(48 hours)