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Onderzoek naar (signaalstoffen van) de voedingstoestand bij patienten met een tumor in de long, borst, prostaat of dikke darm.

Recruiting
Conditions
precachexia, cachexia, cancerprecachexie, cachexie, kanker
Registration Number
NL-OMON24155
Lead Sponsor
VU University Medical Center
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
400
Inclusion Criteria

4.2.1Inclusion criteria for cohort (part 1, not-WMO):

1. Adults (> 18 years);

Exclusion Criteria

1. Ascites (for which treatment is necessary) or serious pitting edema;

2. Chemotherapy treatment in the past month;

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To determine the prevalence of (pre)cachexia (based on the current definition) in patients with advanced cancer scheduled for treatment with chemotherapy.
Secondary Outcome Measures
NameTimeMethod
1. To determine the prevalence of pre-cachexia and cachexia related to the type of tumour (part 1, not-WMO);<br /><br>2. To determine the reproducibility and validity of the measurement of pre-cachexia and cachexia at two consecutive time points (at minimum one week apart from each other) in one patient (part 1, not-WMO);<br /><br>3. To determine whether potential biomarkers of pre-cachexia can be identified in a subgroup of cancer patients with stage III/IV non-small cell lung cancer (part 2, WMO).
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