NCT00099216已完成3 期
Efficacy and Safety of Rivastigmine Capsules in Patients With Probable Vascular Dementia
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 708
- 试验地点
- 63
- 主要终点
- Change in cognition from baseline at week 24
研究概览
简要总结
The goal of this research study is to evaluate the effectiveness, tolerability and safety of rivastigmine capsules in males and females between the ages of 50 and 85 years old with probable vascular dementia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Between the ages of 50 and 85 years old
- •Have contact with a responsible caregiver 3 or more days per week
- •Be male or a female who is surgically sterilized or one year post menopausal
排除标准
- •Current diagnosis of severe or unstable cardiovascular or other diseases
- •Current diagnosis of active, uncontrolled seizure disorder, Parkinson's disease or Alzheimer's disease
结局指标
主要结局
Change in cognition from baseline at week 24
Global clinical impression of change from baseline at week 24
次要结局
- Change in activities of daily living from baseline at week 24
- Change in behavioral symptoms from baseline at week 24
- Change in clinical staging from baseline at week 24
研究者
研究点 (63)
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