NCT04462068已完成不适用
ACE and HLA Genotypes Predict Severity and Disease Progression in Danish Sarcoid Patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Time to initiation of treatment
研究概览
简要总结
Sarcoidosis is a multisystem granulomatous disease of unknown cause histologically characterized by noncaseating granulomas. Genetic factors affect disease course, which is highly variable and difficult to predict.
This study aims to evaluate the predictive value of ACE and HLA genotypes on disease severity and progression in Danish patients with sarcoidosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of sarcoidosis
- •Signed informed consent
排除标准
- •Inability or unwillingness to adhere to the study
- •Inability to give informed consent
结局指标
主要结局
Time to initiation of treatment
时间窗: 1 year from diagnosis
Time to initiation of systemic immunosuppression for sarcoidosis
次要结局
- Change in FEV1(1 year)
- Number of participants with extrapulmonary organ involvement(1 year from diagnosis)
- Change in diffusion capacity(1 year)
- Change in FVC(1 year)
研究者
研究点 (1)
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