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Monitoring Telemedicine Platform in Patients With Anxiety Symptoms and Alcohol Use Disorder

Completed
Conditions
Anxiety Disorders
Alcohol Use Disorder
Depressive Disorder
Interventions
Behavioral: Monitoring with a device
Registration Number
NCT03991650
Lead Sponsor
humanITcare
Brief Summary

The objective of this study is to analyze the physiological patterns of two groups of patients, one control and one with anxiety disorder and alcoholic abuse disorder using sensor data from mobile devices and wearables. This data will be compared to the data presented by three clinical questionnaires: State-trait Anxiety Inventory (STAI), the Alcohol Use Disorders Identification Test (AUDIT), and the Beck's Depression Inventory (BDI-II) in order to determine the feasibility of remote collected data.

Detailed Description

The objective of this study is to analyze the physiological patterns of two groups of patients, one control and one with anxiety disorder and alcoholic abuse disorder using sensor data from mobile devices and wearables. This data, collected by sensors, will be compared to the data presented by three clinical questionnaires: State-trait Anxiety Inventory (STAI), the Alcohol Use Disorders Identification Test (AUDIT), and the Beck's Depression Inventory (BDI-II) in order to determine the feasibility of using remote collected data in routine clinical practice. Furthermore, patient satisfaction with the app will be evaluated after the data collection phase.

This is a unicentric, case-controlled, longitudinal, evaluational, national study with two groups, one control of healthy individuals without symptoms of anxiety or depression, and another experimental group in which participants fulfill the given selection criteria for the trial. There are a total of 60 participants split evenly between the two groups.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
44
Inclusion Criteria
  • 18-65 years of age.
  • Alcohol use disorder (DSM 5) as main substance.
  • Anxiety (STAI > percentile 33) and, if depressive symptoms, not clinically relevant as to accomplish DSM5 diagnostic criteria for mood disorders (major depressive disorder, bipolar disorder...).
  • Having a mobile phone compatible with Android.
  • Sign informed consent.
Exclusion Criteria
  • Mood disorder diagnoses (DSM5).
  • Cognitive deficits that prevent the participation.
  • Active intake of other substances (except for nicotine).

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
ExperimentalMonitoring with a deviceThe recruitment process will be carried out in patients of external consultations and the day hospital of the Addictions Unit at the Hospital Clinic of Barcelona. n=30 patients with Anxiety and Alcohol Use Disorder. The participants will be monitored over the course of one month using the humanITcare app "U-Shine," which will track participant's sociability, device usage, and location frequency using mobile sensors. Participants will also be monitored using a FitBit device to track sleep schedules, heart rate, and step count. During the weekly follow-up, they will have to complete the three clinical questionnaires taken at the initial visit.
ControlMonitoring with a devicen=30 healthy participants will be recruited using social networks and leaflets of information distributed by the research team at the Hospital Cliníc de Barcelona. The participants will be monitored over the course of one month using the humanITcare app "U-Shine," which will track participant's sociability, device usage, and location frequency using mobile sensors. Participants' data will also be monitored with a FitBit device to track sleep schedules, heart rate, and step count. During the weekly follow-up, they will have to complete the three clinical questionnaires taken at the initial visit.
Primary Outcome Measures
NameTimeMethod
Distance travelledOne month

Monitoring of distance travelled using GPS phone

Change in Self-reported Anxiety symptoms assessed with the State-Trait Anxiety Inventory (STAI)One month, questionnaire taken 4 times (1/week)

Taken through the application "Ushine". Participants receive STAI scores ranging from 0-60, 0 being lowest amount of symptoms, and 60 being the greatest amount of symptoms, which are then transformed into percentiles according to age and sex.

Sleep patternOne month

Monitoring of circadian rhythm using a motion sensor Fitbit and cardiac activity sensor

REM sleep timeOne month

monitoring of REM sleep patterns using a motion sensor Fitbit and cardiac activity sensor

Heart RateOne month

monitoring of heart rate using Fitbit sensor

Step countOne month

Monitoring of daily step count using motion sensor FitBit

Mobile device usageOne month

Monitoring how often the patient's mobile device is used, determined by tracking the presence of a signal from their device

Sociability (number of incoming an outgoing calls and text messages)One month

The number of incoming and outgoing calls and text messages will be monitored using the UShine app algorithm

Change in Self-reported Depression symptoms assessed with the Beck's Depression Inventory (BDI-II)One month, questionnaire taken 4 times (1/week)

Taken through the application "Ushine". Participants receive BDI-II scores ranging from 1-63, with a score of 0-13 indicating minimal depression, 14-19 indicating mild depression, 20-28 indicating moderate depression, and 29-63 indicating severe depression.

Change in Self-reported Alcohol Abuse Symptoms assesed with the Alcohol Use Disorders Identification Test (AUDIT)One month, questionnaire taken 4 times (1/week)

Taken through the application "Ushine". Participants receive AUDIT scores ranging from 0-40. A score of 8 or more is associated with harmful or hazardous drinking, a score of 13 or more in women, and 15 or more in men, is likely to indicate alcohol dependence.

Secondary Outcome Measures
NameTimeMethod
Usability of the mobile applicationOne month

Ease of usability of the mobile applications by participants will be scaled using the System Usability Scale (SUS). Final scores range from 0-100. A score of 51 or under means the system has serious faults in usability, a score of 68 means the system usability is about average, and a score of 80.3 or higher means the system usability is considered appreciable.

Satisfaction with the applicationOne month

Participants' satisfaction with the Ushine application will be scaled using the Post-Study Usability Questionnaire (PSSUQ). Scores range from 0-100, 0 being least satisfactory and 100 being the most satisfactory. The PSSUQ has 3 sub-scores representing system usefulness, information quality, and interface quality, also scaled from 0-100. In all score sets, 0 is considered the least satisfactory and 100 is considered the most satisfactory.

Trial Locations

Locations (1)

Hospitcal Clínic de Barcelona

🇪🇸

Barcelona, Spain

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