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Clinical Trials/CTRI/2024/12/078491
CTRI/2024/12/078491
Not yet recruiting
Phase 4

Comparison of Analgesic Efficacy of Ultrasound Guided Retrolaminar Block vs Caudal Block for Paediatric Patients Undergoing Open Inguinal Surgeries: A Non-Inferiority Randomised Controlled Trial

All India Institute of Medical Sciences, Patna1 site in 1 country66 target enrollmentStarted: December 24, 2024Last updated:

Overview

Phase
Phase 4
Status
Not yet recruiting
Sponsor
All India Institute of Medical Sciences, Patna
Enrollment
66
Locations
1
Primary Endpoint
Time to first rescue analgesia

Overview

Brief Summary

Regional anaesthesia for inguinal surgeries in children has attracted increasing interest and different technique like like subarachnoid,caudal,epidural block,wound infiltration,ilioinguinal and paravertebral block have been used with varying success.

In Paediatric surgery caudal block is a low cost,simple and effective procedure for post operative analgesia.

Retrolaminar Block is one of the newer and simpler alternative technique to the traditional caudal block.Drug is deposited into the retrolaminar spacebetween the lamina of T12 and paraspinal muscle.

Caudal block is most common regional anaesthesia technique used for inguinal surgeries in paediatric patients. Caudal block is not free of complications and can include side effects and complications like hypotension,motor blockage,urinary retension,subdural,intravascular or intraosseus injections of the drug,injury to nerve roots and spinal cord infections etc.Retrolaminar block in other hand is less invasive and the target is away from neuroaxis,rendering it potentially safe.

Through this study,we are trying to explorean alternative regional anaesthesia technique that is less invasive with non-inferior analgesic benefit compared to Caudal block.

No RCT has been conducted till date comparing Retrolaminar Block to Caudal block in paediatric patients.

We expect that Retrolaminar Block will provide analgesia non inferior to Caudal block in Paediatric patients undergoing inguinal surgeries.This will help us to inculcate this block as routine practice in our setup in this subset of patients.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant and Outcome Assessor Blinded

Eligibility Criteria

Ages
1.00 Year(s) to 6.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Age 1-6years ASA I and II patients scheduled for inguinal surgeries.

Exclusion Criteria

  • Patients with coagulation disorders Patients hypertensive to study medications Patients with developmental or mental delay Skin lesions or infection at the planned site of needle insertion Congenital vertebral anomalies.

Outcomes

Primary Outcomes

Time to first rescue analgesia

Time Frame: assessment within 24 hours post surgery estimated at 30 minutes, 2 hours, 4 hours, 8 hours, 12 hours and 24 hours.

Secondary Outcomes

  • Intraoperative fentanyl use(Number of patients requiring rescue analgesia in 24hours/till the time of discharge)

Investigators

Sponsor
All India Institute of Medical Sciences, Patna
Sponsor Class
Government medical college
Responsible Party
Principal Investigator
Principal Investigator

Dr Suman Das

AIIMS Patna

Study Sites (1)

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