Copeptin Registry (proCORE)Biomarkers in Cardiology (BIC)-19
Recruiting
- Conditions
- I21Acute myocardial infarction
- Registration Number
- DRKS00008714
- Lead Sponsor
- Rettungsstellen Campi Nord Internistische Notaufnahme CVK
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1000
Inclusion Criteria
•Admission to the Emergency Department or CPU with signs and symptoms consistent with acute coronary syndrome
•Low-to intermediate risk profile (GRACE-score below 140 and a low- to intermediate likelihood of ACS as judged by the treating physician)
•Patients eligible for the early rule-out strategy using combined copeptin and troponin testing at admission, irrespective of biomarker test results and disposition decision
•full-aged patient
Exclusion Criteria
None
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary objective:<br>•One-month all-cause mortality in patients in whom acute myocardial infarction is ruled-out using the early rule-out strategy and who are therefore discharged from the ED.<br>
- Secondary Outcome Measures
Name Time Method Secondary objectives in all patients tested for copeptin and troponin at admission, irrespective of biomarker test results and disposition decision:<br><br>•Diagnosis of acute myocardial infarction<br>•Final hospital diagnoses<br>•Time to discharge/transfer from the ED/CPU<br>•Disposition decision (discharge or admission)<br>•Length of hospital stay<br>•ICU-treatment<br>•Performance of Coronary angiography/ PCI/ CABG<br>•Performance of ECGs, stress testing, imaging<br>•Performance of cardiovascular monitoring<br>•In-hospital mortality<br>•One-month mortality<br>