NCT01420497已完成不适用
Systemic Effects of Epidural Methylprednisolone Injection on Glucose Tolerance in Diabetic Patients
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- glycemic values,
研究概览
简要总结
Several studies have shown that in diabetic patients, the glycemic profile was disturbed after intra-articular injection of corticosteroids. Little is known about the impact of epidural injection in such patients. The goal of this study was double, at first comparing the glycaemic profile in diabetic patients after a unique injection of 80 mg of acetate methylprednisolone either intra-articular or epidural, secondly to compare the amount of systemic diffusion of the drug the after both procedures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •diabetes stable for more than ten days
- •no contraindication for steroids
- •lumbar stenosis
- •articular pain
排除标准
- •unstable diabetes
- •renal insufficiency
研究组 & 干预措施
methylprednisolone,infiltration
Active Comparator
干预措施: intra-articular infiltration (Drug)
epidural injection
Active Comparator
干预措施: epidural infiltration (Drug)
结局指标
主要结局
glycemic values,
时间窗: day 0 to day 15
次要结局
- urinary excretion rate(day 0 to day 15)
研究者
zufferey Pascal
md
Centre Hospitalier Universitaire Vaudois
研究点 (1)
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