Longitudinal Follow up of Patients With Pleural Effusion in South Korea
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
This study aims to evaluate the clinical course of patients diagnosed with pleural effusion and determine various clinical factors and biomarkers associated that can predict the diagnosis and clinical outcome and prognosis of patients with pleural effusion due to specific causes.
详细描述
Patients who presented to Seoul National University Bundang Hospital with pleural effusion would be recruited. Pleural fluid and blood samples would be collected. All patients will receive routine diagnostic procedures and medical care and treatments according to the diagnosis; the original cancer if diagnosed with malignant effusion, and managements for pleural effusion control. Patients would be observed for the clinical course and prognosis up to 3 years without any interventions caused by this study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients presented with pleural effusion
- •Patients who undergo thoracentesis and fluid analysis for diagnosis and management
排除标准
- •Patients who refuse to be enrolled
结局指标
主要结局
Mortality
时间窗: From date of diagnosis of malignant pleural effusion until the date of death, assessed up to 36 months.
Mortality
次要结局
- Disease progression(From date of diagnosis of malignant pleural effusion until the date of first documented disease progression, assessed up to 36 months.)